Thermo Scientific Vanquish VF-D20, Руководство по эксплуатации, Страница: 104 / 182

6 • Operation
Page 104 Vanquish Charged Aerosol Detectors Operating Manual
• When the mobile phase was stored over a period of time, high
background current may be observed. Replace old mobile phase
with freshly prepared mobile phase.
•
If you use the detector for the analysis of complex biological
samples, proper sample preparation is especially important.
•
If you perform a gradient, it is recommended to perform blank
injections with the desired method gradient profile prior to analysis.
This "pre-conditioning" of the column improves the performance of
both, the analytical column and the detector.
6.7.2 Overview of Optimization Parameters
The following table serves as an overview of parameters that influence
the performance of the detector during data acquisition.
Parameter Affects
Filter constant Sensitivity, baseline noise
Evaporation temperature Baseline noise, background current
Power function value Linear range
Data collection rate Peak resolution, disk space, possibly baseline noise
For further information about the parameters, refer to the
Chromeleon
Help .
6.7.3 Data Collection Rate and Filter Constant
The Chromeleon software automatically calculates the best data
collection rate and filter constant, based on the value you enter for the
peak width in the Instrument Method Wizard.
If you want to select a different data collection rate and filter constant,
note the guidelines below.
Data Collection Rate
The data collection rate is the number of data points per second (Hz)
that the Chromeleon software collects from the detector and stores as
raw data.