Thermo Scientific TSQ 8000, User Manual

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Thermo Scientific TSQ 8000 Evo User Guide 31
3
Tuning
Tuning will improve the performance of your TSQ 8000 Evo system. For optimum stability,
you must wait until the power, vacuum, and heaters lights on the front of the instrument are a
solid green. These lights indicate that the instrument has reached vacuum and that it is at the
last set temperature. If the system has been powered off for a period of time (that is, a cold
system), the system components take up to 4 hours to thermally stabilize after reaching the
temperature setpoint. If you did not vent the instrument (that is, the system is hot), the
components take approximately 10 minutes to thermally stabilize after reaching the
temperature setpoint. If you exchanged the ion source without venting, the source
components take approximately 30 minutes to stabilize temperature.
You can tune the TSQ 8000 Evo system by using the TSQ Series Dashboard.
Accessing Auto Tune
 To access Auto Tune choose one of these two methods
• Double-click the TSQ Series Dashboard shortcut on your desktop to open the
TSQ Series Dashboard and then click Auto Tune . See Figure 31 .
Contents
• Accessing Auto Tune
• Tuning the Mass Spectrometer
• Updating Tunes for New RF Lens
IMPORTANT Be sure to give the TSQ 8000 Evo system enough time to stabilize.
Otherwise, you may see mass drift, mass spectral changes, or changes in the fragmentation
of your data.
Note If you are running samples with heavy matrix, running the samples before the
source has had time to stabilize at high temperature will prematurely dirty the ion volume
and optics.