7
•
Maintenance and Service
Page 106
UHPLC System
Operating Manual
7.4
Routine and Preventive Maintenance
Optimum system performance, maximum uptime of the system, and
accurate results can be obtained only if the system is in good condition
and properly maintained.
7.4.1
Maintenance Plan
Perform the maintenance procedures in the table on a regular basis. The
frequency given in the table is a suggestion. The optimum frequency for
maintenance depends on several factors, such as the types and amounts
of samples and solvents used with the system.
Frequency
What you should do...
Daily
•
Inspect the flow connections for signs of leakage or
blockage.
•
When you use buffers or salt solutions, flush the system
thoroughly after use with an appropriate solvent that
does not contain buffers or salts.
Regularly
•
Solvent line filter frits: regularly check the filter frits for
permeability. Replace the filter frits at regular intervals.
This is especially important when using aqueous solvents.
Aqueous solvents may contaminate the filters with algae
and other microorganisms that deposit on the filter frits.
Therefore, also replace the solvents at regular intervals.
Rinse the reservoirs thoroughly before refilling them.
•
Empty the waste container or containers.
•
Inspect the flow connections for damage, such as cracks,
nicks, cuts, or blockage.
•
Check the drain system for blockage (see
). If a leak alarm is triggered or if
a leak is visible, find and eliminate the blockage.
•
Clean the system (see
Cleaning or Decontaminating the
).
•
Check that all warning labels are still present on the
system and clearly legible. If they are not, contact
Thermo Fisher Scientific for replacement.
Annually
Have Thermo Fisher Scientific service personnel perform
preventive maintenance once a year.
7.4.2
Cleaning or Decontaminating the System
Cleaning and decontamination must be performed by qualified
personnel wearing suitable personal protective equipment. Always
observe national and local regulations.
Summary of Contents for thermoscientific Vanquish UHPLC System
Page 4: ...Contacting Us Page 4 UHPLC System Operating Manual ...
Page 28: ...2 Safety Page 28 UHPLC System Operating Manual ...
Page 34: ...3 System Overview Page 34 UHPLC System Operating Manual ...
Page 38: ...4 Unpacking Page 38 UHPLC System Operating Manual ...
Page 82: ...5 Installation Page 82 UHPLC System Operating Manual ...
Page 100: ...6 Operation Page 100 UHPLC System Operating Manual ...
Page 112: ...7 Maintenance and Service Page 112 UHPLC System Operating Manual ...
Page 128: ...8 Troubleshooting Page 128 UHPLC System Operating Manual ...
Page 132: ...9 Specifications Page 132 UHPLC System Operating Manual ...
Page 144: ...11 Appendix Page 144 UHPLC System Operating Manual ...