Millipore Integritest Exacta, Operating And Maintenance Manual

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Integritest

Exacta Filter Integrity Test Instrument
Operating and Maintenance Manual Glossary
269
GLOSSARY
Bubble Point Pressure
Bubble point is based on the fact that liquid is held in the pores of a filter by surface tension and
capillary forces. The Bubble Point Pressure is the minimum pressure required to overcome these forces
and force liquid out of the pores of a membrane filter.
Bubble Point Test
A non-destructive filter integrity test that is based on the fact that liquid is held in the pores of a filter by
surface tension and capillary forces. The Bubble Point test detects the minimum pressure required to
overcome these forces and force liquid out of the pores of a membrane filter. The Bubble Point is most
critical for determining that a membrane is integral and meets specifications. This test procedure is also
useful for determining whether a correct cartridge has been installed in a filter housing.
Click
To press and release a mouse button quickly.
Default Password
Administrator
Default User Name
Administrator
Double-click
To rapidly press and release a mouse button twice without moving the mouse. Double clicking carries
out an action, such as starting an application.
Drag
To move an item on the screen by selecting the item and then pressing and holding down the mouse
button while moving the cursor. For example, you can move a window to another location on the
screen by dragging its title bar.
Diffusion
Diffusion is a migration of a solute from a region of high concentration to a region of lower
concentration. In most integrity tests the solute is air or nitrogen, which diffuses through a wetted
membrane.
Diffusion Test
A diffusion test is based on the fact that under pressure, compressed air or nitrogen flows through the
liquid that is held in the filter’s pores at differential pressures below the bubble point. In small area
filters, this airflow is very slow and often not measurable. But in large area filters, it is significant enough
to measure and provide a sensitive filter integrity test.
Downstream Side
The downstream side is the outlet, or sterile side of the filter through which fluid has passed.