Millipore Integritest Exacta, Operating And Maintenance Manual

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Integritest

Exacta Filter Integrity Test Instrument
Operating and Maintenance Manual Troubleshooting
205
INTRODUCTION
Some of the problems commonly encountered during filter testing can be easily corrected.
Satisfactory solutions, however, are most often derived from:
• careful diagnosis of the problem
•
recording the circumstances related to the failure
•
recording the nature of the failure
•
a systematic approach towards solving the problem
General Troubleshooting Procedure
Determine if the problem is due to the application (i.e., the filter system) or to the operation of
the instrument.
•
This can be determined by conducting a referee integrity test simultaneous with an
instrument test. The simultaneous referee test will give an objective test result that can
verify if the instrument is operating properly.
If there is an application issue check the following:
Table 24: Troubleshooting Testing Problems
Problem Type of Test Impacted Problem Resolution Options
Improper filter wetting
resulting in higher diffusion
values and/or lower bubble
point values.
Bubble Point &
Diffusion
Rewet the filter using flow thru
wetting (See Millipore Wetting Insert
for specific instructions)
Improper filter drying
resulting in high HydroCorr
test values.
HydroCorr Dry the filter (See Millipore
Validation Guide - HydroCorr
Integrity Test Specifications - for
specific instructions)
Temperature variations
resulting in inaccurate test
results.
All Tests Use room temperature test fluid.
Maintain constant temperature
during the test.
Filter contamination
resulting in inaccurate test
results.
All Tests Flush the filter and re-wet.
Also, if the contamination is from
the product being filtered, consider
establishing product bubble point
specifications.
If there is an instrument operation issue, check the following:
• Make sure that the Integritest Exacta instrument is plugged into a properly grounded
wall outlet and that there is power to that outlet.
• Check all pneumatic connections to the Integritest Exacta instrument and make sure all
connectors are firmly attached.
•
Verify that the gas source is connected to the INLET connector on the pneumatic
module and that the gas supply is turned on.
•
Confirm that the gas source is supplying 35–100 psig of clean dry air or nitrogen.