Medonic M16C-US, Руководство пользователя

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Chemotherapy Cytotoxic and immunosuppressive drugs may increase the fragility of the leuko-
cytes, which may cause falsely low WBC counts.
Cryoglobulins Increased levels of cryoglobin may cause elevated levels of WBC, RBC or PLT
counts as well as HGB. Cryoglobulins may be associated with myeloma,
carcinoma, leukemias, macroglobulinemia, lymphoproliferative disorders,
metastatic tumors, autoimmune disorders, infections, idiopathic disease,
aneurism, pregnancy, thromboembolic phenomena, diabetes, etc. The specimen
can be warmed up to 37°C and re-analyzed immediately or a manual WBC, RBC
or PLT count can be performed.
Multiple myeloma The precipitation of proteins in multiple myeloma patients may give falsely
elevated WBC counts.
Large lymphocytes,
atypical lymphocytes,
blasts, and basophils in
excessive numbers The presence of large or atypical lymphocytes, blasts, or an excessive number of
basophils may interfere with the MID cell area which otherwise consists mainly
of monocytes.
Metamyelocytes,
myelocytes,
promyelocytes, blasts
and plasma cells in
excessive numbers The presence of excessive numbers of metamyelocytes, myelocytes,
promyelocytes, blasts and plasma cells may interfere with an accurate
granulocyte count.
Lymphocyte count
interference The lymphocyte count is derived from the WBC count. The presence of
nucleated red cells (NRBC), certain parasites and erythrocytes that are
resistant to lysis may interfere with lymphocyte count.