Media-Mate Plus Operation Manual
25-710-800-O
Fill Time Setting
See
Figure 5-3
.
The Fill Time Setting determines the amount of time the system will allocate to the Fill Cycle
and is dependent on the Delivery Volume Setting. The amount of time allocated must be
sufficient to fill the measure vessels 50-100 mL above the Fill Tube slot. The Fill Time is set
by adjusting the Fill Time Thumbwheel located on the Control Panel.
Low to Moderate Viscosity Media:
1.
Start by setting the Fill Time to the value that corresponds to the Volume Setting in the
table below.
Vol. Setting, mL
250
400
500
600
700
800
900
1000
Fill Time, sec
45
50
55
60
65
70
75
80
2.
Run a Test Cycle (see
Section 7 – “Test Cycle”
) while observing the measure vessels
during the Fill Cycle to see where the fill level is with respect to the Fill Tube slot. The test
media must have the same approximate viscosity as the Dissolution Media that will be
used.
3.
If the actual Fill Level is too high, reduce the Fill Time. If the actual Fill Level is too low,
increase the Fill Time.
4.
Repeat Steps 2 and 3 until the desired characteristics are achieved.
High Viscosity Media:
For high viscosity media it may be necessary to set the Volume Adjustment to one half the
desired delivery volume and run two cycles.
1.
Set Volume Adjustment to one half the desired delivery volume.
2.
Set the Fill Time to two times the value that corresponds to the Volume Setting in the table
above.
3.
Run a Test Cycle (see
Section 7 – “Test Cycle”
) while observing the measure vessels
during the Fill Cycle to see where the Fill Level is with respect to the Fill Tube slot. The
test media must have the same approximate viscosity as the Dissolution Media that will
be used.
4.
If the actual Fill Level is too high, reduce the Fill Time. If the actual Fill Level is too low,
increase the Fill Time.
5.
Repeat Steps 3 and 4 until the desired characteristics are achieved.
Section 7
Operating Instructions
25