Leica BIOSYSTEMS HistoCore BIOCUT, Instructions For Use Manual

Page: 52 / 90

52 Version 1.7, Revision K
Optional Accessories
6
Warning
Insufficient frame conditions for sectioning.
Specimen damage or poor sectioning results, for example, sections alternating in thickness,
compressed, folded or stripped sections.
• Do not continue sectioning if you recognize insufficient sections results.
• Make sure that all prerequisites for appropriate sectioning are met. Refer to the troubleshooting
section of these Instructions for Use for further details.
• If you do not have sufficient knowledge in regards of troubleshooting insufficient sectioning
results consult persons who do have that knowledge, for example, application experts of Leica
Biosystems.
Warning
The remaining broken edge of cassette lid may lead to poor section quality due to insecurely
clamping.
Serious injury of persons.
• When using a cassette whose lid is molded on, make sure that the broken edge left by removing the
lid does not prevent the specimen from being securely clamped – if necessary, the specimen must be
clamped horizontally.
Caution
When using thin-walled cassettes, the cassettes become deformed or insecurely clamped into place,
or other problems because of the clamping system.
Damage to specimen/Delayed diagnosis.
• Be careful when using thin-walled-cassettes. Make sure that the thin-walled-cassettes are clamped
securely in place.
• If the user tries clamping the cassette and realizes that it is not securely clamped into place, use a
more stable one.
Caution
Paraffin deposits on the outside of the cassette can make the universal cassette clamp dirty.
The dirt prevents the cassette from clamping in securely and can lead to sections being too thick or
thin, chattering within the section and, in the worst-case scenario, damage to the specimen.
• Prior to sectioning, the user has to verify that the specimen is clamped securely.
• Remove paraffin deposits from the universal cassette clamp.