Gako Unguator e/s, Operating Instructions Manual

Page: 35 / 52

35
General notes on the UNGUATOR
®
Mixing System
sequence of weighted sample but also if the UNGUATOR ® Jar is considerably underfilled
(e.g. large volumes of powder). These remnants should be transferred into the
UNGUATOR
® Jar using a spatula when about half of the mixing time is complete. The
air should be diminuated again following this process. When using the UNGU-
ATOR
® Disp. Blade, however, there are no niches of flow and no remedial work is
required.
4.2.3 Heating
The heat that develops from the friction between UNGUATOR ® MB and the inside wall
of the UNGUATOR ® Jar is desired as a rule. Decreased viscosity increases the wetability
of powders and speeds the penetration of powder pockets. Even the emulsifying
readiness of fats and oils is promoted by heat. For instance, aqueous hydrophilic
ointments can be produced using the “cold method” using wool fat ointment and water
aa. or also ungt. emulsific. pre-emulsified with a small amount of water (approx. 10 %)
and water ad 70 %.
54 °C/129 °F was the maximum temperature measured after 6 minutes of mixing the
highly pasty preparation made of vaseline and zinc oxide aa under full speed. This
temperature increase is generally safe for the substances employed in the
pharmaceutical field. Ointments of low viscosity only heat slightly [2]. Volatile substances
such as ethereal oils or alcohol do not evaporate from the closed UNGUATOR
®
Mixing
System.
4.2.4 Cleaning the UNGUATOR ® MB
The UNGUATOR
®
MB is normally cleaned with dispensing pulp and, if necessary,
held under a hot water jet and then dried with dispensing pulp. UNGUATOR
®
MBs can
also be cleaned in a dishwasher.
The UNGUATOR ® devices as well as the UNGUATOR ® line products should never be
treated with sharp-edged objects or chafing cleaning agents.
4.2.5 Possible Error Sources to be Avoided
The UNGUATOR ® Jar bottom was not pressed fully down to the stop position prior to
weighing out or filling. First and foremost, it is not imperative to accommodate specifically
light constituents in an UNGUATOR
® Jar of equal weight although the filling volume is
40 % more than the rated volume.