24
General guidelines for the UNGUATOR
®
Mixing System
Crystalline Active Ingredients
We recommend pulverizing active crystalline ingredients in the mortar prior to weighing-
in into the UNGUATOR
®
Jar. Should a solvent for the active crystalline ingredient be
part of the formulation, the ingredients may then also be dissolved in the
UNGUATOR
®
Jar after heating supported by mixing (e.g., urea with water, resorcinol
with glycerin). Then the remaining formulation constituents can be added. The crystalline
substance may also dissolve during the mixing process if the solvent is a constituent
of the foundation ointment. Some cases may require post-processing using an ointment
mill. Afterwards, the ointment should be homogenized using an UNGUATOR
®
.
Waxes, Hydrophilic Ointment, etc.
Pour either 85 °C/185 °F warm water alone or containing the remaining heated
constituents over Cera, Lanette N, etc. in the UNGUATOR
®
Jar. If the mixing temperature
expected is higher than that of the melting temperature of the receiver, it will melt
during the mixing process.
Pour water over the substances and heat them either in a hot-water bath (= 85 °C/
185 °F) or in the microwave, then mix them using the UNGUATOR
®
. Please note that
the UNGUATOR
®
MB cannot go into the microwave. Furthermore, isolated areas of
heat concentration may develop when heating in a microwave. To avoid this, we
recommend coarsely blending the content of the jar during heating using a spatula at
intervals. Please also keep in mind that a microwave will only heat aqueous substances.
Generally it is sufficient to homogenize heated mixtures in three cooling intervals of
six minutes each and apply 10 strokes each using the UNGUATOR
®
at high speed.
Homogenization of solid substances takes slightly longer. The cooling time and hence
the cooling interval can be shortened in the refrigerator or by using a water jacket. The
UNGUATOR
®
MB should remain in the UNGUATOR
®
Jar during the cooling phase.
For emulsions, it makes sense in some cases pregrind ingredients using the whole
fatty phase and a low portion of water with a pregrind program. The remaining water
can then be filled into the UNGUATOR
®
Jar in additional steps when the mixing process
is interrupted. The advantage of pregrinding, where the ground ingredients are
distributed evenly along the UNGUATOR
®
Jar wall, is a relatively fast bonding of the
liquid constituents. This in turn assures an increased tightness of the sealing lips,
even for large UNGUATOR
®
Jars and extended mixing processes.
Summary of Contents for Unguator e/s
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