9.2
Sanitization and cleaning
Sanitization
Sanitization is the use of chemical agents to reduce microbiological contamination to
an acceptable level.
A sanitization procedure is used when there is a need to reduce microbiological levels,
for example between product batches, or when there has been unwanted microbiolog-
ical contamination.
Cleaning-in-place (CIP)
CIP is the removal of every kind of contaminant, protein, lipid, other particles and
microorganisms.
Precautions
WARNING
NaOH is corrosive and therefore dangerous to health. When using
hazardous chemicals, avoid spillage and wear protective glasses
and other suitable Personal Protective Equipment (PPE).
WARNING
In ÄKTA flux s, prevent fluid leakage by tighten the Luer connection
firmly. Do not open the Luer connection by twisting, bending or
vibration. Do not open connectors when pressurized or during on-
going process.
9 Maintenance
9.2 Sanitization and cleaning
168
ÄKTA flux s Operating Instructions 29046893 AG
