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4
Installation
Hardware Installation
2D-LC User Guide
76
Alternative instrument setups for additional functionality
The standard stack setups can be upgraded with additional valves to add
additional functionality.
on page 66 gives an overview of all supported
modifications of a standard 2D-LC instrument. At a time, only one modification is
recommended to ensure correct operation of the instrument. The standard stack
setup uses one column compartment that hosts both the
1
D and
2
D column.
Table 9
List up supported modifications of a standard 2D-LC instrument configuration.
Alternative column compartment
concepts
Comment
Page
A
1
D MCT/TCC hosts column
switching valve
If a 6-position/14-port or 8-position/18-port InfinityLab Quick
Change Valve is used, additional two adapters necessary
(2xG1316-87326, must be purchased separately)
See
B
Setups that contain separate
1
D and
2
D MCTs/TCCs
See
C
Setups in which the
1
D
column is hosted in an
Integrated Column
Compartment (ICC)
Longer capillary (5500-1170) for Quick Connect Fitting at
column inlet or new 0.12x280mm Quick Connect Fitting
assembly (5067-5960) necessary (must be purchased
separately).
See
D
Setup with a MS diverter
valve
See
E
Setup of a
1
D/
2
D Switching
Valve
If a
1
D and
2
D detector is used; not supported with
modifications A-C
See
F
1
D/
2
D Switching Valve w/o
1
D detector
For setups that do not have a
1
D detector, e.g. for certain
LCxLC setups or setups with a QQQ mass spectrometer as a
2
D detector; not supported with modifications A-C
See
G
Single Heart-Cutting
Configuration as Single
Sample Loop Setup
For this setup port 4 and port 5 of the 2D-LC Standard must
be used to connect the single loop while the bypass capillary
is installed at the other position (Port 1 and 8) (for instance
see application G4245A ProtA-SEC Kit).
See