CoolSculpting® Elite
System User Manual
ZELTIQ Clinical Studies
CS-UM-CM3-02-EN-D
57
Table 20: Applicator Placement Methods
Reference
Treatment Area
Placement of the Applicator
Treatment
Cycles (n)
Bernstein & Bloom,
2017
Submental and
submandibular
areas
Bilateral treatment cycles with 20% overlap
in the center of the submental area.
52
Single cycle placed in the center submental
area.
2
Kilmer, Burns, &
Zelickson, 2016
Submental area
Single cycle placed in the center submental
area.
119
Leal Silva, Hernandez,
Vazquez, Leal Delgado,
& Blanco, 2017
Submental area
Single cycle placed in the center submental
area.
30
Lee, Ibrahim, Arndt,
& Dover, 2018
Submental and
submandibular
areas
Bilateral treatment cycles with 30% overlap
in the center of the submental area.
Applicator is placed 1 to 2 cm from inferior
aspect of mandible, in sequence.
2
Li, DaSilva, Canfield,
& McDaniel, 2018
Submental and
submandibular
areas
Single cycle placed in the center submental
area.
1
Bilateral treatment cycles with overlap in the
center of the submental area.
2
Suh et al., 2018
Submental and
submandibular
areas
Bilateral treatment cycles with 30% overlap
in the center of the submental area.
20
References
Published papers
1. Bernstein EF, Bloom JD. Safety and Efficacy of Bilateral Submental Cryolipolysis With Quantified
3-Dimensional Imaging of Fat Reduction and Skin Tightening. JAMA Facial Plast Surg. 2017;
19(5), 350-357.
2. Leal Silva H, Hernandez EC, Vazquez MG, Leal Delgado S, Blanco AP. Noninvasive submental
fat reduction using colder cryolipolysis. J Cosmet Dermatol. 2017; 1-6.
3. Lee NY, Ibrahim O, Arndt KA, Dover JS. Marginal Mandibular Injury After Treatment With
Cryolipolysis. Dermatol Surg. 2018; 1-3.
4. Li MK, DaSilva D, Canfield D, McDaniel DH. Use of 3-Dimensional Imaging in Submental Fat
Reduction After Cryolipolysis. Dermatol Surg. 2018; 889-892.
5. Suh DH, Park JH, Jung HK, Lee SJ, Kim JH, Ryu JH. Cryolipolysis for submental fat reduction in
Asians. Journal of Cosmetic and Laser Therapy. 2018; 24-27.
