C-2
Solvent Considerations
Introduction
Clean solvents
Clean solvents provide these benefits:
•
Reproducible results
•
Operation with minimal instrument maintenance
A dirty solvent can cause these issues:
•
Baseline noise and drift
•
Blockage of the solvent filters with particulate matter
Solvent quality
Use HPLC-grade solvents to ensure the best possible results. Filter solvents
through 0.45-µm filters before use. Solvents distilled in glass generally
maintain their purity from lot to lot; use them to ensure the best possible
results.
Preparation checklist
The following solvent preparation guidelines help to ensure stable baselines
and good resolution:
•
Filter solvents with a 0.45-µm filter.
•
Degas the solvent.
•
Stir the solvent.
•
Keep in a place free from drafts and shock.
Water
Use water only from a high-quality water purification system. If the water
system does not provide filtered water, filter it through a 0.45-µm membrane
filter before use.
Содержание 1500-Series
Страница 14: ...xiv Table of Contents ...
Страница 32: ...1 18 Introduction ...
Страница 50: ...2 18 Installing the HPLC Pump ...
Страница 84: ...3 34 Installing Options and Accessories ...
Страница 108: ...4 24 Preparing for Operation ...
Страница 160: ...A 14 Safety Advisories ...
Страница 184: ...C 16 Solvent Considerations ...