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Rev. 03 / 02.2021
AB3200
Operation
Required validation steps:
■
Evaluation of a potential hazard, such as the overheating of the sample
or sample container, gas formation from the sample, breakage of the
sample container due to mechanical, thermal or chemical overload.
To do this, the device parameters are to be increased in small incre-
ments in order to be able to notice potential hazards early enough.
■
Repetition: Due to repeated runs, the rotor might increasingly heat up,
which can no longer be compensated by the cooling unit.
If such a sequence of runs is planned, the developed protocol must be
tested for this to see whether repeated executions can lead to the
device dangerously overheating or whether the device must first reach
its original temperature again between two runs.
■
Check of the desired effect on the sample.
Personnel:
■
Authorized skilled personnel with special instruction
1.
Define the starting parameters:
NOTICE
The runtime must be selected depending on the
process, but should not exceed 30 minutes.
Very fluid samples can heat up very strongly under cer-
tain circumstances, which could result in the sample
container bursting. Therefore, increase the duration
and/or speed of the run gradually when developing a
new method and observe the heating of the sample.
During the validation of an application, the cooling unit
of the device must be active.
2.
Select a start-up level between
‘5’ and ‘9’; the braking level should
always be set to
Chapter 7.2.2 ‘Start-up and run-down parame-
−
If the process is thermosensitive, you should pre-
−
For frequently recurring processes, we recom-
mend that you save a program for
this
Chapter 7.1.2 ‘Save programs (STO 1-99)’
3.
Monitor the device until the set speed has been
reached. Check whether unbalance can be observed
through the sight glass in the device lid.
Start the run by pressing the
[START] key.
