Waters Quattro Premier XE, Operator'S Manual, Page: 36 / 86

3-8 Operating in APPI, APCI, and Dual APPI/APCI Modes
6. Click the Analyser tab.
7. Set the parameters to the values shown in the following table.
* The value stated for Multiplier is typical; in practice, you should use
the value determined by the Waters Field Service Engineer during
installation of the instrument.
8. Click to start the nitrogen flow.
9. On the APPI+ Source tab, observe the Desolvation and Cone gas flows,
and confirm that they have stabilized and are correct.
10. Click Press for Operate, and confirm that the instrument status
indicator is green.
11. On the Tune window APPI+ Source Tab, click Switch Lamp On, and
confirm that the Lamp readback is green.
12. Load the sample syringe with sample. In this example, naphthalene
(concentration 100 pg/µL) is used.
Recommended Tune window Analyser tab parameters (MS scan)
Parameter Recommended value
Analyser
LM Resolution 1 15.0
HM Resolution 1 15.0
Ion Energy 1 1.0
Entrance 30
Collision 3
Exit 30.0
LM Resolution 2 15.0
HM Resolution 2 15.0
Ion Energy 2 1.0
Multiplier* 650
Collision Cell Pressure (mbar) 0