EuroFlow EF and EF/B
Biological Safety Cabinet
UM-EFAB-EN10.doc
54
The UV-light must be cleaned regularly with alcohol (70%). Put on gloves and switch of the
cabinet and let the UV-light cool down before cleaning. After cleaning the UV-light tube must be
dried before using it.
7.3
Guideline for cleaning of cytotoxic contaminated surfaces (EF/B only)
CYTOTOXIC DANGER
When cytotoxics are used, see
§2.5 Cytotoxic danger (EF/B only) on page
10.
Only the responsible safety officer (biological safety officer or the responsible
examiner) can decide if this procedure is valid or not. Additional standard
operation procedures can be necessary.
In the “contract of employment agreement” of Dutch hospitals of June 2004 a guideline is given
for cleaning of cytotoxic contaminated surfaces.
Summary of this guideline:
Cabinets contaminated with cytotoxics are normally cleaned with a 1% solution of
Natriumdodecylsulfat (SDS-solution CAS-no. 151-21-3) in demineralised water, as described in
§7.1 Cleaning the installation on page 51
.
In addition to this cleaning procedure it is recommended to clean the cabinets surfaces with a
70% Ethyl alcohol solution (ethanol) CAS-no. 64-17-5.
This can be necessary to ensure sterile conditions for example against bioagentia.
To complete this process gas disinfection can be necessary.
Exceptions
A few cytotoxics have a different cleaning procedure.
Example 1:
Cytotoxic
CAS-no. Recommended
cleaner
Azathioprine 446-86-6
Bleomycine 11056-06-7
Daunorubicine(Daunomycin) 20830-81-3
Doxorubicine 23214-92-8
Epirubicine 56420-45-2
Fluorouracil 51-21-8
Idarubicine 58957-92-9
Mixantron (Mitoxantrone)
65271-80-9
Vinblastine 865-21-4
Vincristine 57-22-7
Vinorelbine (Navelbine)
71486-22-1
250 ppm Hypochloriet (Sodium
Hypochlorite) CAS-no. 7681-
52-9.
Example 2:
Cytotoxic
CAS-no.
Recommended
cleaner
