Waters ACQUITY UPLC I-Class Series, System Manual

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1.6 Mass spectrometry........................................................................................................................17
1.7 System components......................................................................................................................17
1.7.1 Binary solvent manager (BSM)............................................................................................18
1.7.2 Sample manager-FTN (SM-FTN) ........................................................................................18
1.7.3 Sample manager-FL (SM-FL)..............................................................................................19
1.7.4 Column heater (CH-A) .........................................................................................................19
1.7.5 30-cm Column heater (optional) ..........................................................................................19
1.7.6 Column manager (optional) .................................................................................................20
1.7.7 Column heater/cooler (optional) ..........................................................................................20
1.7.8 Column Module Switch Box (optional).................................................................................20
1.7.9 Sample organizer (optional).................................................................................................21
1.7.10 FlexCart (optional) .............................................................................................................21
1.7.11 Column technology ............................................................................................................21
1.7.12 Detection............................................................................................................................22
1.8 For additional information..............................................................................................................22
2 Performance optimization........................................................................................24
2.1 General guidelines ........................................................................................................................24
2.2 Dispersion .....................................................................................................................................25
2.3 Carryover ......................................................................................................................................26
2.4 Contamination ...............................................................................................................................26
2.5 Reproducibility...............................................................................................................................26
2.6 Cycle time (between injections) ....................................................................................................27
2.7 Preventing leaks............................................................................................................................27
2.7.1 Installation recommendations for fittings .............................................................................27
2.8 Sample preparation.......................................................................................................................41
2.8.1 Particulates ..........................................................................................................................41
2.8.2 Matching sample diluents ....................................................................................................41
2.9 Solvent recommendations.............................................................................................................41
3 System preparation ..................................................................................................42
3.1 Powering-on the system................................................................................................................42
3.2 Opening the console .....................................................................................................................43
April 4, 2018, 715005704 Rev. A
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