• Pump and sample manager design enhancements to minimize dispersion and reduce cycle
time
• Flexible column management options to support different column lengths and automated
switching of up to six columns in independent temperature zones
• An optional sample organizer to expand sample capacity
1.2.1 Software features
1.2.1.1 Quantum Synchronization
Introducing a low-pressure sample into the high-pressure fluid stream during injection causes a
pressure pulse that can affect chromatographic results. The Quantum Synchronization feature
reduces the effect of this pressure pulse. The sample manager and solvent manager
communicate to automatically coordinate the injection sequence, enabling the solvent manager to
provide additional pressure at the exact moment the sample manager switches its injector valve
to the inject position, to introduce the low-pressure sample.
1.2.1.2 Gradient Smart Start
Before each sample injection, a sample manager typically performs wash sequences and then
aspirates the appropriate sample volume. When these tasks are completed, the solvent manager
begins to deliver the gradient to the injection valve. The dwell volume of the system, which affects
the amount of time required for this gradient to reach the column, can be a significant component
of the overall cycle time.
The Gradient Smart Start feature adjusts when an injection is made relative to when it starts. In
this way, when you transfer methods, the feature compensates for differences in dwell volume
between chromatographic systems. Moreover, it automatically coordinates all pre-injection
operations, minimizing delays that would increase the overall cycle time. In doing so, the feature
makes it possible to begin gradient operation before or during the sample manager's pre-injection
functions, resulting in significant time savings.
1.2.1.3 Wash Plungers
Precipitated material that remains on the solvent manager’s pump plungers can damage the high-
pressure seals. The Wash Plungers function washes the seals and plungers with seal wash
solvent, to remove any precipitate. You can use the Wash Plungers function as needed, or run
the function as part of the No-Flow Shutdown feature.
Tip:
The Wash Plungers function is not available when the module is operating.
April 4, 2018, 715005702 Rev. A
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