Thermo Scientific ISQ EC, Operating Manual

Page: 145 / 232

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Operation
ISQ EC and ISQ EM Mass Spectrometer Operating Manual Page 145
Parameter Description
Use This Detector Select the check box to enable the
currently installed detector.
Installed Probe Type Indicates the installed probe type. For an
ISQ EC MS, the only choice is HESI, for an
ISQ EM MS, the choices are HESI and
APCI.
Method Source Type Set this to the source type for the
method you are developing. This does
not need to be the installed source type,
although you can only run methods for
the installed source type.
More Robustness – More Sensitivity Selects whether more sensitivity or more
robustness is desired.
Less Volatile Mobile Phase – Highly Volatile
Mobile Phase Slider is used to select whether the
mobile phase is volatile or nonvolatile
Thermally Stabile Analyte – Thermally Labile
Analyte Slider is used to select whether analyte is
stable or labile (unstable).
Ionic Analyte in Mobile Phase – Non-Ionic
Analyte in Mobile Phase Slider is used to indicate if analytes are
ionized in the mobile phase.
Total Pump Flow Amount of liquid that flows from the LC
(mL/min)
Instrument Flow Percentage of the total pump flow that
goes to the MS. This can be changed by
using the Split Flow parameter in
Instrument Configuration.
Table 9: APCI Source parameters: Easy view
The MS instrument method editor will look similar to Figure 80 below. The
bottom pane is only available if fraction collection mode is selected in the
instrument configuration.