Thermo Scientific Dionex UltiMate 3000 Series, Operating Instructions Manual

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UltiMate 3000 Series:
NCS-3500RS and NCP-3200RS
Operating Instructions Page 109
• In an UltiMate 3000 system, some components are made of PEEK. This polymer has
superb chemical resistance to most organic solvents.
However, it tends to swell when in contact with trichlormethane (CHCl
3
), dimethyl
sulfoxide (DMSO), or tetrahydrofuran (THF). In addition, it is attacked by concentrated
acids, such as, sulfuric acid and nitric acid or a mixture of hexane, ethyl acetate, and
methanol. In both cases, capillaries may start leaking or they can burst. Swelling or attack
by concentrated acids is not a problem with brief flushing procedures. For more
information about the chemical resistance of PEEK, see the table in section 12.1
( → page 247).
• Before switching from buffer to organic solution, rinse the pump thoroughly with
deionized water.
• When switching to another solvent, ensure that the new solvent is miscible with the one
contained in the pump. Otherwise, the pump can be damaged; for example, by
flocculation.
• When replacing solvents, make sure that the solvents are miscible. Mix immiscible
solvents with an intermediate solvent (for example, isopropanol) to replace them step-by-
step.
• After operation, rinse out buffers and solutions that form peroxides.
Important: Neither recycle the solvent nor use methanol from aluminum
reservoirs. This may impair the performance of the seals.
Important: Thermo Fisher Scientific déconseille de recycler les solvants ou
employer du méthanol stocké dans des réservoirs en aluminium.
Ceci peut affecter les performances des joints.