Blackrock Microsystems NeuroPort Instructions For Use Manual Download Page 1

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Manufacturer
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www.blackrockmicro.com

Revision 1.00 / LB-1070 – NeuroPort Biopotential Signal Processing System IFU – 05/2021
© 2021 Blackrock Microsystems, LLC

NeuroPort
Biopotential Signal
Processing System

Instructions for Use

Summary of Contents for NeuroPort

Page 1: ...y UT 84108 USA P 1 801 582 5533 F 1 801 582 1509 www blackrockmicro com Revision 1 00 LB 1070 NeuroPort Biopotential Signal Processing System IFU 05 2021 2021 Blackrock Microsystems LLC NeuroPort Biopotential Signal Processing System Instructions for Use ...

Page 2: ...ntraindications 7 Warnings 7 Precautions 7 Symbols 8 Specifications 11 Neural Signal Processor 11 Front End Amplifier and Power Supply 12 System Requirements 13 System Description 13 NeuroPort System 14 Hardware 17 Neural Signal Processor NSP 17 Neural Signal Amplifier 20 Amplifier Power Supply APS 21 Cables 22 Accessories 23 Headstages 23 Digital Neural Signal Simulator DNSS 23 Software 24 Centra...

Page 3: ... 32 Analog Output Continuous Monitor 32 Analog Output Spike Monitor 32 Analog Output Sine Waveform 33 Analog Output Custom Waveform 33 Analog Output Triggering 34 Digital Input 34 Digital Output 35 Digital Output Monitor Electrode 35 Digital Output Timed 36 Digital Output Triggered 36 Serial I O 36 Global Settings 37 Filters 37 Auto Thresholding 38 Spike Sorting 38 Tools Menu 40 Adaptive Filtering...

Page 4: ...de Options 46 File Storage 47 TOC Interface 47 2 x Interface 48 File Storage Options 48 Digital Oscilloscope 49 Trigger Type 50 Digital Filter Editor 51 Activity Map 52 Signal to Noise Ratio 53 Neural Modulation 54 Impedance Tester 55 Crosstalk 56 N Trode 57 Spike Display 58 Add Comment 58 nPlay Server 58 Spike Sorting 59 Histogram Peak Count Automatic 59 Hoops Manual 59 Manual PCA 60 k means PCA ...

Page 5: ...Channel on the Digital Oscilloscope 64 Configure Raster Plot 65 Change Electrode Map Create a Map File 66 Setup 68 Hardware Setup 68 NeuroPort System 68 Software Setup 68 Installing Central Software Suite 68 Setting up the Ethernet Connection 68 Cleaning Maintenance and Disposal 70 Cleaning 70 Maintenance 70 Disposal 70 Magnetic Resonance 70 Troubleshooting 71 Return Merchandise Authorization RMA ...

Page 6: ...neural signals including noise cancellation digital filtering simultaneous extraction of spike and field potentials and manual and automatic online spike sorting The NeuroPort Biopotential Signal Processing System is not a monitoring system No physiological alarms are provided The acquisition and display of biopotential signals is for the interpretation and use of the clinician Intended Use Indica...

Page 7: ...roPort System in the presence of flammable anesthetic agents Do not use the NeuroPort System for any use other than its listed intended use Avoid strong static discharges from sources like televisions or computer monitors because it can damage the electrical components of the system Keep the NeuroPort System away from liquids Contact with water shower spray or wet surfaces can lead to the patient ...

Page 8: ... Community 5 1 3 Date of Manufacture Indicates date of manufacture and is accompanied by a date 5 1 4 Use by Date Indicates the date after which the medical device is not to be used 5 1 6 Catalog Number Indicates the manufacturer s catalog number so that the device may be identified For Blackrock Microsystems it is called the Part Number PN 5 1 7 Serial Number Indicates the manufacturer s serial n...

Page 9: ...r to consult the instructions for use for important cautionary information such as warning and precautions that cannot for a variety of reasons be presented on the medical device itself IEC 60417 2002 DB Graphical Symbols for Use on Equipment Reference Symbol Title Meaning 5007 On Power To indicate connection to the mains at least for mains switches or their positions and all those cases where saf...

Page 10: ...g the various parts of an equipment or of a system to the same potential not necessarily being the earth ground potential e g for local bonding 5036 Dangerous Voltage To indicate hazards arising from dangerous voltages 5333 Type BF Applied Part To identify a type BF applied part complying with IEC 60601 1 IEC 60101 1 2012 Medical Electrical Equipment Basic Safety and Essential Performance Referenc...

Page 11: ... bit digital outputs BNC with programmable monitoring functions One TTL output BNC sampling synchronization output port Analog Outputs Four 5 V 600 ohm 16 bit outputs Audio Outputs Two 1 5 V line level outputs PC Interface 1 Gbps Ethernet Power Requirements 110 VAC 60 Hz 6 0 A 240 VAC 50 Hz 3 0 A Line Noise Serviceable Fuses 5 x 20mm 250V 1 6A Slow Blow Compliance Standards IEC 60601 1 IEC 60601 1...

Page 12: ...A max Analog to Digital Conversion 16 bit digital output with 0 25 µV per bit resolution Common Mode Rejection Ratio 90 dB at 50 60 Hz Common Mode Input Range up to 3 0 V between inputs and ground Differential Input Range up to 3 0 V between electrode and reference inputs Maximum Input Voltage Range up to 5 0 V between any input and ground Crosstalk 1 LSB for all configurations Filter Characterist...

Page 13: ...tions listed below are the minimum required by the software to run Blackrock supplies an optional Host PC that is configured and tested by our engineers before it ships with your NeuroPort system Please contact sales blackrockmicro com for more information Microsoft Windows 7 x64 or Windows 10 x64 AMD or Intel 2 0 GHz Dual Core CPU 4 GB of RAM 1x Gbps Ethernet interface card 1 TB 3 Gbit s SATA II ...

Page 14: ...Revision 1 00 LB 1070 NeuroPort Biopotential Signal Processing System IFU 2021 Blackrock Microsystems LLC 14 NeuroPort System ...

Page 15: ...e transmitter manufacturer and d is the recommended separation distance in meters m Field strengths from fixed RF transmitters as deter mined by an electromagnetic site surveya should be less than the compliance level in each frequency rangeb Interference may occur in the vicinity of equipment marked with the following symbol NOTE 1 At 80 MHz and 800 MHz the higher frequency range applies NOTE 2 T...

Page 16: ...the NeuroPort system as recommended below according to the maximum output power of the communications equipment Rated maximum output power of transmitter W Separation distance according to frequency of transmitter m 150 kHz to 80 MHz 80 MHz to 800 MHz 800 MHz to 2 5 GHz 0 01 0 12 0 12 0 23 0 1 0 38 0 38 0 73 1 1 2 1 2 2 3 10 3 8 3 8 7 3 100 12 12 23 For transmitters rated at a maximum output power...

Page 17: ... be programmed through the software or one of the supplied Software Development Kits SDKs Multiple NSPs may be synchronized for recording signals from a very large quantity of electrodes Power switch It is used to turn the NSP ON and OFF The LED above the switch will illuminate blue when the unit is on Note On NSP PN 7530 PN 9650 and PN 10411 this switch is a momentary switch to power down the NSP...

Page 18: ...5 0 V analog output BNC connectors can be used to send monitoring signals or stimulus waveforms to other connectors Audio Output The system sends a 1 V line level audio signal of the selected data channel to two BNC ports Left and Right channeled respectively and one 3 5mm female stereo audio connector simultaneously Digital Outputs Four single bit digital BNC outputs can be programmed for monitor...

Page 19: ...Revision 1 00 LB 1070 NeuroPort Biopotential Signal Processing System IFU 2021 Blackrock Microsystems LLC 19 NSP PN 4176 NSP PN 7530 NSP PN 9650 NSP PN 10411 Figure 4 NSP Back ...

Page 20: ...se contact Blackrock Microsystems support at sales blackrockmicro com Fiber optic Link This port connects to the Amplifier using a fiber optic cable An LED to the right of the connector turns green when a link is established and turns yellow when the link is broken Mains Power Entry This supplies main power to the NSP and is required to power and operate the NSP Mains Power Switch Power switch use...

Page 21: ...t of the same bank If channels on all banks are to be electrically measured with respect to a common reference this reference needs to be connected to the reference input on every bank Additionally four 6 pin APS banks provide power 5V to the headstage and can deliver 130 mA of combined current from the Amplifier The ground pins on every bank are tied together For best results the Amplifier should...

Page 22: ...ons for any inadvertent shorting turn off the APS and turn it back on to reset the error Cables In addition to the above hardware components the system also comes with a few cables Note that standard power cables for the NSP and Front End Amp Power Supply are included but not shown below The fiber optic cable is used to connect the Front End Amplifier to the Neural Signal Processor the Ethernet ca...

Page 23: ...ise it is recommended to keep direct electrode connections shorter than 20 cm 8 inches For longer connections headstages from Blackrock Microsystems are recommended Headstages allow microelectrodes with impedances up to 5 MΩ at 1kHz and cables up to 6 feet in length Which analog headstage to select is dependent on the connector type on the electrodes These connector types and the selection process...

Page 24: ...often the fastest way to visualize overall system function If spike sorting rules are defined the spikes belonging to different units will be displayed in different colors Double click any channel to display the Single Neural Channel Window Raster Plot displays the occurrence of spike events on many channels over time All channel types may be shown in this window Continuous traces and comments can...

Page 25: ...visualization of N Trode groups The Spike Display at the top of the window shows spikes on each channel The Peak Valley panel is used to define spike units for the group The Continuous Data Display shows the full signal from the group Oscilloscope visualizes the signal acquired by any channel Use this window to view measure and compare signals with custom triggers Digital Filter Editor is a MATLAB...

Page 26: ...ad digital filters in the xml format created by the Digital Filter Editor Save System Settings Saves the channel settings currently set in Hardware Configuration Save Sorting Rules Saves spike sorting parameters Save PCA Basis Saves PCA basis vectors calculated during spike sorting Close Applications Closes Central Suite programs while leaving the hardware running Hardware Standby and Close Closes...

Page 27: ...pike unit classifications used to recognize and separate neural spike events Do Not Log Sort Changes Disables sort change logging Log Sorting Changes on Record Will automatically log the spike sorting model the signal to noise ratio summary and the crosstalk summary if rebuilt during recording Log Sorting Changes Always Will log the spike sorting model the signal to noise ratio summary and the cro...

Page 28: ...the Edit Properties menu Auto Impedance Interface Configures impedance testing for the Patient Cable or CerePlex headstages Autoload System Settings Upon opening Central the ccf file input below will be loaded If the field is left blank Central will prompt the user to select a ccf file Windows The Windows menu contains system and software summary information as well as shortcuts to Central applica...

Page 29: ...ettings heading at the bottom of the left pane Channel Sorting Central Suite supports front end amplifier inputs as well as analog digital and serial inputs and outputs Channels can be viewed in icon list or full row detail modes selectable in the tool bar on the toolbar Each channel can be sorted based on function under Signal Types or based on physical location under NSP Channels Configuring Cha...

Page 30: ...nit of analog signal measurement displayed for reference External Gain Gain value of the headstage All Blackrock systems use a gain of 1 Enable Line Noise Cancellation Enables cancellation of 50 or 60 Hz noise Estimate Time Constant The period over which line noise parameters are determined LNC Method Selects software or hardware line noise cancellation Filter Select a digital filter to apply to c...

Page 31: ...ware reference Enable Spike Processing Allow detection of spike events on channel Filter Filter selection for spike event processing Graphical Chooser Allows visualization of the spike processing filter in place Threshold Value Voltage threshold for classification of a spike event in mV RMS Threshold Set parameters for auto threshold calculation Sorting Algorithm Set the sorting algorithm for a ch...

Page 32: ...tor will scale a user input signal into a plus or minus 5 V output signal Input Range Input voltage range displayed for reference Output Range Output voltage range displayed for reference Track Most Recently Selected When enabled the channel selected in Spike Panel Single Neural Channel or Raster Plot view is used as the monitor input Channel An analog output channel configured as a spike monitor ...

Page 33: ... sine wave Frequency Hz Frequency of the output sine wave Offset mV DC offset of the output sine wave Wave Number Select which of five waveforms are configured and used Trigger Triggering options are explained on Page 34 Analog Output Custom Waveform An analog output channel configured as a custom waveform generator will produce a user defined waveform on a user defined trigger stimulus Wave Numbe...

Page 34: ...to low A digital input bit must be selected Spike Unit Waveform triggers when a sorted unit is detected on a defined channel NeuroMotive ROI Triggers when a subject enters or exits a selected region of interest Extension Waveform triggers based on custom extension code loaded onto hardware Digital Input Digital input properties are accessed from the left side bar of the Hardware Configuration Wind...

Page 35: ... indicate if digital pins D8 D15 changed from LOW to HIGH 8 bit strobe 8 bit bit falling edge Reads bits 0 7 on the rising edge of the strobe pin and bits 8 15 indicate if digital pins D8 D15 changed from HIGH to LOW Digital Output The Digital Output Window is accessed from the left side bar of the Hardware Configuration Window and allows the user to set the properties of the digital outputs Digit...

Page 36: ...n triggered mode will send a pulse when the selected trigger stimulus occurs Digital Input Rising Edge Waveform triggers when a user defined digital input pin transitions from low to high A digital input bit must be selected Digital Input Falling Edge Waveform triggers when a user defined digital input pin transitions from high to low A digital input bit must be selected Spike Unit Waveform trigge...

Page 37: ...preceding a threshold crossing Line Noise Frequency Hz The line frequency of the system either 50 Hz or 60 Hz LNC Reference Channel The reference channel used to compute system line noise The extracted line noise template for each channel can be viewed in Single Neural Channel when the Raw LNC button is checked Filters This window displays the details of a selected digital filter in a bode plot an...

Page 38: ...le Manual PCA k means PCA DBSCAN PCA and Histogram Peak Count Each method is described below Manual PCA Manual PCA uses principle component analysis to generate a feature point for each spike event The user manually defines unit classifications by drawing an ellipsoid around each cluster of feature points within the feature space Wave Basis Size The number of waveforms to use to calculate the PCA ...

Page 39: ...d waveforms are broken down into high frequency and low frequency components Each spike event is plotted on an axis composed of these two components A histogram is constructed and clusters are estimated by determining peaks and valleys Valley Percentage A valley is identified at a height less than the first peak height times the valley percentage value Close Peak Percentage The second peak is iden...

Page 40: ... function Continuous Spike Sorting Selecting this item will continuously adjust the spike sorting statistics including the splitting and merging of units This is not recommended for use while recording Build PCA Builds the PCA basis vectors for all channels with PCA based spike sorting Assisted Spike Sorting Enable k means DBSCAN or all PCA methods for spike sorting Adaptive Filtering Recorded sig...

Page 41: ...egions When any single unit spike is detected within the N Trode the signals from all component electrodes are saved and registered as events The Central Suite supports multiple N Trode sets containing up to four electrodes each Multiple single channels are linked and spike sorting occurs on the N Trode as a single entity To define N Trode groups open a group and add channels to it with the arrow ...

Page 42: ...nction Double click any channel to display the Single Neural Channel window The layout and graphical settings of the grid and individual channels can be changed in the right click menu or the toolbar A map file can be applied to the display to change the spatial arrangement of the channels on the screen to match the electrode array in use If spike sorting rules are defined the spikes belonging to ...

Page 43: ...n Selected Channels Individual or groups of channels can be viewed by selecting Open Selected Channels in the right click menu or the top menu bar Show Labels Display channel information on the cursor Refresh Screen Manually refresh the spike panel display Magnify Current Channel Toggle mouse hover magnification Spike Scale Adjust the visual amplitude of displayed spikes Broadcast Channel Selectio...

Page 44: ...ete Remove selected channel from the plot Move Up Down Move selected channels through the channel list Continuous Data Scale Set the amplitude of continuous signals Show Neural Events Display neural events as impulses on the raster plot Show Continuous Data Display continuous channel trace Raw Toggle Toggle between filtered continuous and raw data Update Refresh the display Sort Sort channels in t...

Page 45: ...menu Channel Selector Scroll through channels Channel Properties Open the Channel Properties window Persist Spikes When selected the last detected spikes will remain in the wave viewer for sorting View Tool Tip Display time and amplitude values at the cursor position View Continuous Toggle the Continuous Data Display View Classification Toggle the Online Classification Display Broadcast Channel Se...

Page 46: ...Select unit definitions to remap combine or map to noise 3D PCA On line Spike Classification If manual PCA is selected spike sorting is performed using online PCA analysis within the PCA space PCA spike sorting can classify up to five different signals per channel each selected signal receives a separate color An ISI Histogram is also displayed for each classified spike A user can sort an individu...

Page 47: ... which indicates the date and time of the recording For example 20110124 152145 indicates that the data file was recorded on January 24 2011 at 3 21 45 PM GMT System settings will be saved in the same folder as the data file File Splitting Splitting large files into smaller sizes may aid offline analysis File size limit is defined in the View Options menu To disable file splitting check the disabl...

Page 48: ...omatically incrementing the data file names with an appended numeral File Specification Choose between the different file specifications It is advised to always use the most current specification File Storage Options After opening the File Storage Window options can be found under View menu Enable Sync Pulse Send a unique waveform pattern every 14 seconds and repeat patterns hourly Invert Sync Pul...

Page 49: ...nels may be viewed per instance of the oscilloscope Channel Selection Select any channel from the drop down menu Color Selection Select a color for either trace Settings Open the properties window for the selected channel Invert Invert the trace for a given channel Trace Amplitude Modifying the sliders for each channel will change the signal amplitude The top slider changes the range and the lower...

Page 50: ...isplay waveforms on the oscilloscope Auto Continuous signal will be displayed until the trace crosses the user defined trigger level When the trigger level is crossed the trace will pause for two seconds then resume until another triggering event occurs Normal The trace will freeze as soon as the trace crosses threshold until the trace crosses the trigger level again in which case the screen will ...

Page 51: ... Runtime to be installed Contact support blackrockmicro com for a copy of this software Filter type and corner frequencies are defined in the Editing Tools section on the left side of the window The stability of the filter is shown in the Filter Status section below The Bode Plot and the Nyquist Plot of the designed filter are displayed Once the filter parameters are set click on Save to save the ...

Page 52: ...oothing adds steps between events and non events both between channels and over time Maximum Scale Range Set the maximum value of the color scale in spikes per second Scale Eccentricity Skews the mapping of spike rate to color towards high or low values Time Constant Set the time constant controlling activity decay Pause Pause the display until unchecked Reset Clear current activity data and refre...

Page 53: ...oise ratio for units on each channel It also displays the signal to noise ratio as a function of time which allows changes in signal quality to be monitored This information can be saved as a tab delimited text file and opened in Excel or a compatible program for further analysis In the example below the SNR for elec11 unit 3 is 9 50 meaning that the signal is 9 5 times bigger than the noise Figur...

Page 54: ...ems LLC 54 Neural Modulation Neural Modulation displays a histogram of changes in firing frequency over time The Modulation Index is the variance of the histogram entries and covers a range of 0 to 12 0 A range of 2 to 5 is considered normal when recording neural signals Figure 39 Neural Modulation ...

Page 55: ...tion properly the impedance mode must be selected in Central click Tools Options Auto Impedance Interface Either mode begins by asking for array information including the serial number implantation date type of sterilization and comments Special equipment may be required for impedance measurements Contact Blackrock Microsystems sales at sales blackrockmicro com for more information Figure 40 Auto ...

Page 56: ...tion The Crosstalk Diagnostic feature will display each channel as green yellow or red indicating the amount of unique signal on each electrode Green No cross correlation to any other channel was found Yellow Possible cross correlation found Examine signals closely to determine best use Red High levels of cross correlation found Consider removing these channels from recordings Figure 41 Crosstalk ...

Page 57: ...he other N Trode channels When an event is detected on a channel within an N Trode all other N Trode channels record a neural event with the same timestamp spike width samples pre threshold samples and refractory period see Global Settings Central supports multiple N Trode sets containing up to four electrodes each Define N Trode configurations in the Hardware Configuration window or within the N ...

Page 58: ...manipulate the N Trode GUI Spike Display Spike Threshold Adjust the voltage threshold for spike detection on all channels Clear Clear the spike display Automatic clearing will occur to maintain the number of spikes shown in the drop down menu Show Spikes Select which spike units to display Add Comment The Add Comment feature allows the user to add a timestamped text comment to the Neural Event fil...

Page 59: ...y take a few minutes and must be repeated for each experimental session Each time the sorting is rebuilt new classifications are calculated based on current data Note To save Histogram Peak Counts sorting rules in Central click File Save Sorting Rules To load Histogram Peak Counts sorting rules click File Load Sorting Rules Hoops Manual 1 Open the Hardware Configuration window and select channels ...

Page 60: ... sorting rules in Central click File Save System Settings To load Hoops sorting rules click File Load System Settings Manual PCA 1 Open the Hardware Configuration window and select channels of interest 2 Right click and choose Properties or click on the Properties icon 3 Choose Manual PCA from the spike sorting drop down menu 4 Open Single Neural Channel and select the desired channel 5 Make sure ...

Page 61: ...m Settings To save PCA basis vectors click File Save PCA Basis To load PCA basis vectors click File Load PCA Basis k means PCA 1 Open the Hardware Configuration window and select one channels of interest Multiple channels may be selected and sorted at once 2 Right click and choose Properties or click on the Properties icon 3 Choose k means PCA from the spike sorting drop down menu 4 From the Centr...

Page 62: ...is pressed down so you can see the units window 6 Click on the Feature tab 7 Click on Build PCA By default the program needs 250 waveforms to build the PCA basis vectors The time required to record 250 waveforms will depend on your spike rates and may take several minutes You can modify the number of waveforms used in Hardware Configuration Spike Sorting 8 Wait for feature points to be generated C...

Page 63: ...ters will be available in the drop down menu under Hardware Configuration for analog inputs Renaming Multiple Channels Central has a built in automatic channel naming scheme with several parameters 1 Open Hardware Configuration 2 Select non contiguous channels by holding down Control while selecting or select a range of channels by holding down the Shift key and clicking the upper and lower bounds...

Page 64: ...les you to visualize two channels at high resolution Setting a trigger can improve visualization of signals To setup the oscilloscope follow the instructions below 1 Open Central and in the main window click the Oscilloscope 2 Enable Trace 1 and or Trace 2 3 Select a channel for each trace from the drop down menu 4 Click on Settings to verify all channel settings Make sure a sampling rate is selec...

Page 65: ...t crosses the trigger level To capture another threshold crossed trace click on Single again Configure Raster Plot The Raster Plot can display the occurrence of spike events or continuous signals for many channels over time The plot can be configured to match your experimental setup 1 Begin by removing all channels from the display using the clear all button 2 Open the choose channels display and ...

Page 66: ...location assignments of each channel A sample map file is included below 8 Channel NSP map file demo Data is as follows C olumn r ow b e l c 0 based column from left to right r 0 based row from bottom up b bank name values can be A B C or D l label used to rename channels in Central Comments begin with First non comment line is the Mapfile description 8 Channel NSP mapping 0 1 A 4 elec08 1 0 A 8 e...

Page 67: ...hannel is connected to The fifth column is optional and defines the label for the channel In the example above the first line indicates that the channel on bank A pin 4 is named elec08 and it s located on the 1st column from left 0 and the 2nd row from the bottom 1 The last line indicates that the channel on bank A pin 1 channel 1 is named elec04 and it should be placed on the 4th column 3 from le...

Page 68: ...tral Suite through Programs and Features in Windows Control Panel 2 Run the Central Suite installer msi from the installation CD or Blackrockmicro com 3 Install the MATLAB Compiler Runtime from the supplied installation CD or Blackrockmicro com 4 Blackrock recommends that a dedicated PC be used to run Central Refrain from installing any additional software or connecting the PC to the internet Sett...

Page 69: ...e NSP using a business class 1 Gbps network switch with QoS feature For other PCs connected using a network switch IP addresses should increment such as 192 168 137 2 192 168 137 3 etc Note For your reference the NSP s IP address is 192 168 137 128 Figure 52 Network Connections Window Figure 53 Local Area Connections Properties Figure 54 IPv4 Properties ...

Page 70: ...debris on the exterior connectors ports may be removed with compressed air Maintenance The system does not require any scheduled maintenance or calibration For issues with the system see the troubleshooting section and or RMA sections below Disposal All devices both used and unused should not be disposed with household waste Return to a recycling point for electric and electronic devices Magnetic ...

Page 71: ...nt Change which electrode is used as reference to better remove common noise or use noise cancellation in Central to remove noise from the recording System Not Turning On No Lights on LCD of Neural Signal Processor Secondary Power Supply Switch is Off Verify the position of the power switch in the rear of the Neural Signal Processor is ON NSP Is Stuck in Initializing LCD of Neural Signal Processor...

Page 72: ...et port is capable of gigabit operation Check ethernet connection and reduce CPU load Allow Central to communicate through the firewall Return Merchandise Authorization RMA In the unlikely event that your NeuroPort system needs to be returned to Blackrock for repair or maintenance do not send any equipment back without a Return Merchandise Authorization Number An RMA number will be issued to you b...

Page 73: ...by disclaims all other warranties including without limitation the implied warranties of merchantability fitness for a particular purpose and non infringement of third party patent or other intellectual property rights Blackrock shall not be liable for special indirect incidental punitive exemplary or consequential damages including without limitation damages resulting from loss of use loss of pro...

Page 74: ...ease provide the product description product number software version lot number complainant s name and address and the nature of the complaint Issues or Questions www blackrockmicro com technical support support blackrockmicro com U S 1 801 582 5533 Notice to the user and or patient that any serious incident that has occurred in relation to the device should be reported to the manufacturer and the...

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