OM0303
Rev 5 July/2021
Page 64 of 108
Areas/Correction Factors for Calculations
Cabinet Size
3" (76mm) Constricted Window
Access Area
8" (203mm)
Window Access Opening
8" (203mm)
Window Correction Factor
400E
.97
(.090)
2.58
(.239)
1.20
500E
1.22
(.113)
3.24
(.240)
1.18
600E
1.47
(1.37)
3.91
(.363)
1.18
7.6 HEPA Filter Leak Test
In order to check filter and filter seal integrity, the HEPA filter media and seals must be directly accessible, by the measuring
instrument. There are three separate sets of HEPA filters that must be checked: Primary HEPA Prefilter, Secondary HEPA
Supply Filter and Secondary Exhaust HEPA Filter.
7.6.1
Primary HEPA Prefilters
This section will explain how to check the integrity of the HEPA prefilters that are located beneath the work
surface. In order to properly validate these HEPA filters a challenge material must be introduced (PAO, or a similar
challenge that can be detected using a particle counter) upstream of the primary filters. The scanning wand is
used to dispense the particle challenge directly at a small section of each filter in order to help isolate the position
of any leaks.
The following is needed to help check the filter integrity:
Particle counter
Particle generator
Sliding window should never be opened unless interior is known to be free of
hazardous drug residue or appropriate precautions are taken per facility
Standard Operating Procedures (SOP’S).
NOTE
: Cabinet should be on and running throughout the filter replacement process.
Hazardous Drug
Using appropriate PPE, surface decontaminate or clean cabinet workzone interior including both sides of the
worktray. Remove worktray from cabinet and be sure window is at nominal work height of 8” (203mm).
Remove
the stainless steel plug from the front of the base. Insert tube for particle counter and secure with low-residue tape.
CAUTION
!
Содержание LabGard NU-581-400E
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