OM0303
Rev 5 July/2021
Page 37 of 108
6.6 Hazardous Drug Decontamination Procedures
This procedure is intended to provide guidance following a spillage and/or periodic maintenance, testing or relocation of
the cabinet. Additional guidance can be provided by the CETA document CAG-005-2007 found at the CETA website:
www.CETAinternational.org.
6.6.1
Preparation
Prior to beginning decontamination activity, personnel should wear proper personnel protection equipment (PPE)
i.e. Tyvek
1
isolation gown, 2 pair of Nitrile gloves and a full-faced HEPA filtered respirator. All protective garments
should be contained in 4 mil plastic bags and labeled for disposal as chemotherapy waste after completion of the
procedure. For the purpose of this procedure, detailed procedures for cleaning a Class II BSC can be found in the
2006 ASHP Technical Assistance Bulletin
ASHP Guidelines on Handling Hazardous Drugs
2
.
6.6.2
Procedure
a. Make sure that the cabinet remains in operational mode with internal blower on.
b. Open the hinged or sliding view screen and secure in the full open position.
With the view screen in the full open position, personnel protection
is compromised and a full faced HEPA filtered respirator must be
worn.
c. Clean all readily accessible surfaces of the cabinet.
d. Remove perforated metal diffuser screen from the underside of the supply HEPA filter and place on the
cabinet work tray.
NOTE:
Depending on the model, the diffuser screen is secured to the cabinet by #8-32 screws or
1/4" - 20 acorn nuts, 3 places. It is purposely a tight fit and is secured to the back wall with
projecting threadless studs.
e. Clean both sides of the perforated metal diffuser screen and remove it from the cabinet.
f.
Lift the cabinetwork tray, clean both sides and remove it from the cabinet.
g. Remove the front perforated grill, place on the cabinet floor and clean both sides.
Remove from cabinet.
h. Clean work tray supports.
i.
Working from top to bottom, clean all inside surfaces of the cabinet. Take care
not
to wet the HEPA filter.
If liquid has collected in the plenum drain, aspirate it using IV tubing into an evacuated container. Label
the evacuated container for disposal as chemotherapy waste.
j.
Clean the plenums drain area and wipe dry.
k. If the cabinet requires maintenance and/or replacement of the HEPA filters, the operation should be
halted at this point to allow trained personnel to complete replacement of the HEPA and/or maintenance
action required.
6.6.3
Assembly
a. Replace front (if removed) grill.
b. Replace the work tray and carefully tighten the thumbscrews.
c. Replace perforated metal diffuser screen over the underside of the supply HEPA filter.
d. Wipe down all exposed surfaces of the work area with 70% isopropyl alcohol.
e. Prepare for aseptic operation.
CAUTION
!
Содержание LabGard NU-581-400E
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