48
XCell
TM
ATF System with C410:V3 Controller
User Guide
PRV2 Max (psi)
-1
PRV2 Min (psi)
-12
6.3.5 Press Accept Changes.
6.3.6 Go to the MAIN screen enter:
Field
VALUES
P-FLOW Status
SP (Lpm)
12
E-FLOW Status
VALUES
SP (Lpm)
12
6.3.7 Note that PV and PRV fields are populated
6.3.8 Check all XCell
TM
ATF System connections.
6.3.9 Press START
Once the system begins to cycle, Note the following
•
The deviation of Actual Flow from Set Flow. The deviation between the two
should be small. Following few cycles, the Actual and Set Flows should be
similar.
•
Note if in P-Flow block, Actual Cycle Time field is flashing Orange or Red; the
same for the E- Flow block, Actual Cycle Time field. If not flashing, the system
is functioning properly. If flashing remains, stop the controller and recheck all
entries and connections than restart. If problem persists check the following:
a.
The ∆P between
PRV1-P2 should be greater than
P-Pressure Offset
and
∆
P
between PRV2-P2 should be less than
E-Pressure Offset
. If not, manually
lower PV in small increments.
b.
Flow is too rapid- A flow that is too rapid during the Exhaust Cycle can be
readily detected on the P2 trend by a rapid decline in pressure following a
stable pressure profile. (The Pump exhausts too rapidly followed by a rapid
pressure drop). Decrease PV2 or PRV2 to decrease flow as a corrective
measure.
•
Select the P2 trend in the MAIN screen and observe P2 profile, The P-Pressure
Offset and the E-Pressure Offset should be apparent.
Any adjustments in P2 trend on the Main screen are performed from the P2 TREND
screens
6.4
Examples
XCell
TM
ATF System process control settings will depend on the process requirements.
Each user or process may have its own unique requirements. Hopefully, the example
provides a guideline, to assist the users, in selecting and optimizing operating
conditions.
When working with an XCell
TM
ATF System connected to an unpressurized vessel, refer
to Figure 1 for an overview of positioning the Filtration Assembly, P-Box and E-Box
relative to the bioreactor.
