XCell ATF Series, User Manual

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Contents
1. Description of XCell TM ATF System and Process ...................................................................... 1
1.1 XCell TM ATF System Pump Cycle .................................................................................... 2
1.2 XCell TM ATF System Control Scope and Objectives: ....................................................... 4
1.3 XCell TM ATF Pump Housing and Controller Pairings ...................................................... 4
1.4 XCell TM System Interconnectivity Drawing .................................................................... 5
2. Utility Requirements ............................................................................................................. 6
3. Size and Weight .................................................................................................................... 7
4. XCell™ ATF Pump Housing Assemblies ................................................................................... 8
5. C410:V3 Controller Layout .................................................................................................. 17
5.1 General Layout ............................................................................................................. 17
5.1.1 Filtration Assembly ............................................................................................ 18
5.2 Primary Pneumatic Services......................................................................................... 19
5.3 Primary Electric Services .............................................................................................. 21
5.4 Signal ............................................................................................................................ 21
5.5 C410:V3 Ethernet set-up and Connectivity ................................................................. 21
6. C410:V3 Controller Process and Control .............................................................................. 22
6.1 Interface and screens ................................................................................................... 22
6.2 Control Overview ......................................................................................................... 45
6.3 Start-up ........................................................................................................................ 46
6.4 Examples ...................................................................................................................... 48
7. Hollow Fiber Module and Diaphragm Replacement ............................................................. 50
7.1 Separating the Filtration Assembly from the bioreactor: ............................................ 50
7.2 HFM removal: .............................................................................................................. 50
7.3 HFM insertion: ............................................................................................................. 51
7.4 Screen Module replacement: ...................................................................................... 52
7.5 Diaphragm replacement: ............................................................................................. 52
7.6 Assembly ...................................................................................................................... 53
7.7 Use ............................................................................................................................... 53
8. Sterilization ........................................................................................................................ 53
8.1 Preparation of Filtration Assembly for autoclaving ..................................................... 53