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ACQUITY Arc system
The ACQUITY Arc system, which provides true plug-and-play method compatibility
for HPLC and UHPLC separations, can replicate established assays developed on older
HPLC platforms. Using Arc Multi-flow-path technology, the system accepts methods
from any HPLC platform, emulating the dwell volume and mixing behavior of the
original. The system can also improve productivity by pairing with UHPLC column
technology without requiring manual adjustment. Lastly, the ACQUITY Arc system
accepts UPLC methods that have undergone adjustment for larger particle sizes.
1.1 Features of the ACQUITY Arc system
The ACQUITY Arc system performs validated assays using quaternary-based LC
technology that adjusts for the differences between HPLC and UPLC separations.
These are among the system's features and capabilities:
• Pump and sample manager design enhancements that minimize dispersion and
reduce cycle time
• Plug-and-play method compatibility with HPLC or UHPLC
• Direct programing of gradients, in units of pH and ionic strength, using
Auto•Blend Plus technology to vary composition, eliminating the need to manually
prepare mobile phases
• Automatic management of gradient start time and pre-injection steps, in parallel,
minimizing cycle time and maximizing sample throughput
• Automatic counteraction of differences in system dwell volume without the need
to alter gradient-table inputs
• Continuous needle cleansing during the run, minimizing carryover
• Column heater and column heater/cooler options that ensure method
repeatability from lab to lab
• Integrated column-selection valve options that provide fast column changes
• Optical detection options that maximize HPLC and UHPLC performance
• Extend the dynamic range of sample analysis with mass spectrometer options
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