￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭￭
1 Introduction
850 Professional IC–Anion – MSM-HC – MCS – LP Gradient
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1
1 Introduction
1.1
Instrument description
The instrument
850 Professional IC – Anion – MSM-HC – MCS – LP
Gradient
(2.850.2230) is one of the model versions of the Professional IC
line of instruments manufactured by the Metrohm Company. The Profes-
sional IC line of instruments is distinguished by:
￭
the
intelligence
of its components, which are able to monitor and
optimize all functions and to provide documentation according to FDA
requirements.
￭
its
compactness
.
￭
its
flexibility
. A suitable model version exists for every application.
Individual instruments can be converted, expanded or modified to cre-
ate a different instrument as needed.
￭
its
transparency
. All components are easily accessible and arranged in
a clear manner.
￭
its
safety
. Chemicals and electronics are separated and a leak sensor is
integrated in the wet end.
￭
its
environmental compatibility
.
￭
low noise emission
.
The instrument is operated with
MagIC Net
software. It is connected via
a USB connection to a PC on which MagIC Net is installed. The software
automatically recognizes the instrument and checks its functional readi-
ness. MagIC Net controls and monitors the instrument, evaluates the mea-
sured data and administers it in a database. The operation of MagIC Net is
described in the online help or in the tutorial for MagIC Net.
The low pressure mixing valve and two additional eluent degassers in the
lower area of the instrument are used for the controlled mixing of up to 3
eluents.
The instrument contains the following components:
Eluent degasser
The eluent degasser removes gas bubbles and dissolved gases from the
eluent. For degassing, the eluent flows into a vacuum chamber through a
special fluoropolymer capillary.
Low pressure gradient
Up to three different eluents can be mixed with the low pressure gradient.
The mixing takes place in the low pressure zone, i.e. before the eluent is
conveyed to the high pressure pump.