Function and design
HICO-VARIOTHERM 550
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In addition to the described side effects in adults during
therapeutic hypothermia, in newborns the following must still also
be considered:
•
(severe) pulmonary hypertension,
•
viscosity increase (clotting disorders and manifest thrombosis)
in polycythaemia (polycythaemia > 65 % first after
hemodilution),
•
thrombocytopenia,
•
arterial hypertension,
•
hypovolemia,
•
PPHN (Persistent pulmonary hypertension of the newborn),
•
bradycardia
•
haematuria
In pediatrics, after perinatal hypoxia/ischaemia, moderate
hypothermia of 33 - 34 °C within the first 6 hours for a period of
48 – 72 hours causes a significant improvement in the
neurological outcome between the age of 12 – 18 months.
The inclusion criteria for newborns is
≥ 36 weeks of pregnancy
and in ages < 6 hours with acute encephalopathy and peripartum
asphyxia results.
The exclusion criteria is in ages > 6 hours and newborns "in
extremis".
Contraindications
•
advanced malign disease
•
persistent state of shock / cardiopulmonary instability
•
pregnancy
•
coma of different origin
•
body temperature below 30 °C during the recording
•
time interval when starting resuscitation and cardiac arrest
above 15 minutes
•
application distal of arterial cross-clamping
