Bioer GeneQ Thermal Cycler, Manual, Page: 9 / 33

Gene Q Thermal Cycler Chapter 1 Introduction
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c) Thermoelectric Cooling Thermal Cyclers
These are the most advanced thermal cyclers by far. A thermoelectric cooling thermal cycler also
has a metal block at its center (like a compressor cooling thermal cycler). A thermoelectric module
closely attached to the block’s outside bottom accomplishes Block heating and cooling. Not only
does this device inherit such features as high intelligent level and small size from a compressor
cooling thermal cycler, but it also has higher temperature control accuracy and heating/cooling rate,
thanks to the module’s excellent temperature response characteristics. And the temperature
uniformity across the block is much better compared to a compressor cooling thermal cycler
because the modules are distributed over the block’s outside bottom.
During its early development, a thermoelectric module was not able to withstand rapid and frequent
heating or cooling for long. With improved workmanship, this difficulty has been overcome. Current
long service-life thermoelectric modules have the capability of enduring such harsh conditions in a
thermal cycler. As result, thermoelectric cooling thermal cyclers have gradually dominated the
market.
5 Features of the Gene Q Thermal Cycler
The Gene Q Thermal Cycler is a thermoelectric cooling thermal cycler. It features:
a) Reliable and stable operation, because the thermoelectric module is manufactured via the
U.S. ITI’s thermoelectric cooling technique and the Japanese quality management model;
b) High heating/cooling (heating rate ≥5.0 ℃ /sec., and cooling rate ≥4.0 ℃ /sec.), which greatly
reduces experimental time;
c) Automatic temperature ramp control, which allows different heating/cooling ramp settings
so that the device can emulate other thermal cycler’s temperature control process;
d) Automatic temperature and time increments/decrements during cycling program
execution,
e) optimizing the PCR amplification conditions;
f)
Automatic link among files, allowing a complex PCR amplification program to be executed;
g) The soak mode at a temperature up to 4
℃
without human interference, after normal
cycling program execution;
h) Instant inspection of total execution time and remaining execution time;
i)
Optional heated lid, preventing the sample in a centrifugal tube from evaporation, which
makes paraffin oil unnecessary and operation more convenient, and reduces the sample
processing time;
j) Auto-restart in case of power failure, restoring the data before interrupting and continuing
to perform the previously interrupted program.