Appendix
Page E-16
Operator’s Manual PiCCO
2
Version 3.1
PDR = 100
x
ln2 / t½
where
PDR
=
Plasma disappearance rate (%/min)
t½
=
Half life of ICG-PULSION
R15 = C
15
/ C
0
x
100 %
where
R15
=
ICG Retention rate after 15 minutes (%)
C
15
=
Concentration of ICG-PULSION after 15 minutes
C
0
=
Back-extrapolated concentration of ICG-PULSION at Time 0
5.7
Oxygenation
ScvO
2
= [HbO
2
x
100] / [HbO
2
+ Hb
Des
]
where
ScvO
2
=
Central Venous Oxygen Saturation (%)
HbO
2
=
Concentration of oxygenated haemoglobin (g/dl)
Hb
Des
=
Concentration of deoxygenated haemoglobin (g/dl)
DO
2
= 1.34
x
Hb
x
SaO
2
x
PCCO
x
10
where
DO
2
=
Oxygen delivery (ml/min)
Hb
=
Concentration of haemoglobin (g/dl)
SaO
2
=
Arterial Oxygen Saturation (%)
PCCO
=
Continuous Pulse Contour Cardiac Output (l/min)
DO
2
I = 1.34
x
Hb
x
SaO
2
x
PCCI
x
10
where
DO
2
I
=
Oxygen Delivery Index (ml/min/m
2
)
Hb
=
Concentration of haemoglobin (g/dl)
SaO
2
=
Arterial Oxygen Saturation (%)
PCCI
=
Pulse Contour Cardiac Output Index (l/min/m
2
)
VO
2
= 1.34
x
Hb
x
(SaO
2
–
ScvO
2
)
x
PCCO
x
10
where
VO
2
=
Oxygen Consumption (ml/min)
Hb
=
Concentration of haemoglobin (g/dl)
SaO
2
=
Arterial Oxygen Saturation (%)
ScvO
2
=
Central Venous Oxygen Saturation (%)
PCCO
=
Continuous Pulse Contour Cardiac Output (l/min)