Gambro Cobe Spectra, Справочник по основам

Страница: 49 / 245

Introduction
COBE
®
Spectra™ Apheresis System • Essentials Guide 2-23
When you change a pump flow rate during a Single-Needle procedure,
the Spectra system may alert you that the the pump flow rate you
entered was too high by displaying an alarm or decreasing the pump flow
rate you entered. The reason the pump flow rate is too high is due to the
limitations the system places on a Single-Needle procedure.
For a Single-Needle (SN) procedure, the upper limit on pump flow rates
depends on several factors:
•
The Spectra system limits average inlet pump flow rates to
65 mL/min for SN ELP and SN LRS procedures, and to
60 mL/min for SN TPE procedures. The limit for SN LRST
procedures in 70 mL/min.
•
The Return Flow Controller’s maximum return pressure of
450 mm Hg for SN ELP, SN LRS, and SN LRST procedures, and
400 mm Hg for SN TPE procedures limits the return flow rate
during SN procedures.
•
The SN Draw phase’s instantaneous inlet pump flow rate may be as
much as 100 mL/min for SN ELP and LRS procedures,
130 mL/min for SN LRST procedures, and 150 mL/min for SN
TPE procedures.
For more information on Single-Needle flow control, see “Single-Needle
Flow Control” on page 6-5.
The upper limits on the average inlet pump flow rates indicate that
Single-Needle procedures can take approximately twenty percent longer
than Dual-Needle procedures.
Modes of Operation
During each apheresis procedure, the Spectra system cycles through five
distinct modes of operation: Load Set, Prime, Run, Rinseback, and
Unload Set. A sixth mode, Diagnostics, usually occurs at the end of the
Prime mode, but you can also select it at other times. For more
information about modes, states (steps within modes), and how you can
change the mode if necessary, see “The CHANGE MODE Key” on
page 5-17.
Load Set
During Load Set mode, the the pump cartridges retract and the system
loads the tubing into the pumps.
Prime
During Prime mode, the AC line fills with anticoagulant and the tubing
set fills with saline as air exits the set. Pumps turn, and valves open and
close to test the function and integrity of the system. You must complete
Prime before starting a procedure.
Run
During Run mode, the system automatically operates the pumps and
centrifuge at appropriate speeds, and controls valve positions to perform
the apheresis procedure according to configured parameters. The system
also generates alarms when necessary, which pause the system and alert
you of a potential problem (see Chapter 12, “General Alarms and
Troubleshooting,” for more information).
Rinseback
Once the apheresis procedure reaches the chosen endpoint, the system
prompts you to begin Rinseback mode. The system flushes the tubing
set with saline and returns RBCs to the donor or patient.