Waters 1500-Series, Operator'S Manual

Page: 145 / 188

Identifying chromatographic problems 6-11
Baseline noise
cycling, short-term
(30 to 60 sec)
Fluctuating flow rate Degas eluent. Try
repriming the pump(s). If
necessary, check flow
accuracy of the pump(s).
Inadequate eluent
blending
Install a mixer as shown
on page 3-8 .
Power source (short- or
long-term cycling)
Disconnect other
instruments on the power
line; try a different wall
outlet; have line voltage
checked; use power
conditioner.
Radio frequency noise
(short- or long-term
cycling)
Eliminate interference.
Baseline noise
cycling,
long-term (for
1 hour)
Ambient temperature
fluctuations
Stabilize ambient
temperature.
Integrator or recorder
faulty
Inspect integrator or
recorder for excessive
baseline noise.
Correcting chromatographic problems (Continued)
Symptom Possible cause Corrective action