ThermoFisher Scientific HERASAFE 2025 Operating Instructions Manual Download | Manualshive

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HERAsafe 2025

50161258

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33

Start-up

Initial Operation

Prior to initial operation, the safety cabinet must be subjected to an installation test. Correct
assembly and installation performed by the operator are essential for good start-up.

Installing Unit and Accessories

Herasafe 2025:

Device without stand:



Place the device without stand onto a sufficiently stable substructure so that the
weight of the device frame does not rest upon the drain pan.



Remove the protective foil from the table tops and arm rests.

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Summary of Contents for HERASAFE 2025

Page 1: ...Valid 30 08 2017 50155204 ...

Page 2: ... GmbH This regulation does not apply to reproductions for in plant use Trademarks Thermo Scientific is a brand of Thermo Fisher Scientific All other trademarks mentioned in the operating instructions are the exclusive property of the respective manufacturers Thermo Electron LED GmbH Robert Bosch Straße 1 D 63505 Langenselbold Germany Thermo Electron LED GmbH is a subsidiary company of Thermo Fishe...

Page 3: ...upplied 15 Acceptance Inspection 15 Transport Lock and Device Packaging 15 Chapter 3 Installation of the Device 17 Ambient Conditions 17 Room Ventilation 18 Correct Location 18 Installation in Series 18 Connections 19 Power Receptacles 19 Transport 20 Chapter 4 Unit Description 21 Overall View 21 Safety System 22 Filter System 24 Controls and Display 25 Sample Chamber Access 26 Device Interfaces 2...

Page 4: ... Display Air Inlet Velocity 47 Display Downflow Velocity 47 Setting UV Disinfection Time 48 Start UV Disinfection 49 Cancel UV Disinfection 49 Rocker Switch 49 Moving the Front Window 50 Chapter 7 Preparation 51 Hygiene Preparations for the Sample Chamber 51 Preparing the Sample Chamber 51 Response to Failure Messages 52 Work Rules 52 Chapter 8 Shut down 55 Interrupting an Operation 55 Shutting th...

Page 5: ...nce 63 Inspection 63 Service 63 UV Lamps 63 Sample Chamber Illumination 64 Replacing the Front Cover Seal 64 Retrofitting and Repairs 64 Chapter 11 Disposal 65 Disposal Procedure 65 Chapter 12 Technical Data 67 Chapter 13 Device Log 73 Chapter 14 Certificate of Decontamination 75 ...

Page 6: ...Table of Contents 6 50161258 Herasafe 2030i Maxisafe 2030i ...

Page 7: ...ols and Display 25 Figure 6 Access through Front Cover 26 Figure 7 Access through Front Window 27 Figure 8 Supply Interfaces 28 Figure 9 Workspace Illumination 29 Figure 10 UV Lamp Unit 30 Figure 11 Working Area on the Workplate Armrests 31 Figure 12 Stand Installation 34 Figure 13 USB Port 36 Figure 14 Explanation of the Display components 39 Figure 15 Rocker switch 49 Figure 16 Sitting Posture 5...

Page 8: ...Figures 8 50161258 Herasafe 2030i Maxisafe 2030i ...

Page 9: ...536376 Service 0800 1 112110 Fax Sales Service 0800 1 112114 E Mail info labequipment de thermofisher com Enquiries from Europe Middle East and Africa Tel 49 0 6184 90 6940 Fax 49 0 6184 90 7474 Enquiries from North America Phone 1 800 879 7767 1 800 879 7767 Fax 1 828 658 0363 Enquiries from Latin America Phone 1 828 658 2711 Fax 1 828 645 9466 Enquiries from Asia Pacific Phone 852 2711 3910 Fax ...

Page 10: ...be carried out only by trained and authorized expert personnel The contents of the operating instructions are subject to change without further notice Concerning translations into foreign languages the German version of these operating instructions is binding lease Keep these operating instructions close to the unit so that safety instructions and important information are always accessible Should...

Page 11: ... non observance may cause serious or even lethal injuries Is used if non observance may cause medium to minor injuries or damage NOTE is used for hints and useful information Valuable raw materials can be reused Observe operating instructions Biohazard USB interface CE conformity mark confirms conformity according to EU Directives GS sign TÜV Nord ...

Page 12: ...5 AH at mainboard 2 x T 16 AH Equipment Fusing inside the electronic module X20 connection for an external fan X21 connection for a solenoid valve X22 connection for an external component Armrest installation UV lamp At the supply lines for measurement of the raw air concentration by leakage testing of the filter ...

Page 13: ...th the requirements of safety levels 1 2 and 3 The unit must not be operated as a Class II safety cabinet if no repeat test is performed after changes to the installation conditions or after modifications to the technical system the alarm system of the device has issued a failure message and the cause for the failure has not been repaired The alarm system must not be tampered with or disabled If a...

Page 14: ...f the following standards and guidelines IEC 61010 1 2010 EN 61010 1 2010 EN 12469 2000 EN 61326 1 2018 Low Voltage Directive 2014 35 EU EMC Directive 2014 30 EU RoHS directive 2011 65 EU WEEE directive 2012 19 EU China EEP Hazardous Substances Information http www thermofisher com us en home technical resources rohs certificates html ...

Page 15: ... components and accessories are listed as separate items in the delivery document Acceptance Inspection After the device has been delivered immediately check the device for completeness for possible damage If the delivery is incomplete or if you detect any transport damage to the device contact the forwarding agency and Thermo Electron LED immediately Transport Lock and Device Packaging Do not tra...

Page 16: ... Delivery 16 50155215 HERAsafe 2025 Chapter 2 ...

Page 17: ...Fisher Scientific BSC specialist The location must be equipped with an appropriate ventilation system see Room Ventilation on page 18 The temperature within the room must be between 10 C and 40 C The power supply voltage should not vary by 10 from its nominal value Transient overvoltage peaks shall not exceed the usual range prevailing within the AC power supply grid The nominal transient overvolt...

Page 18: ...le locations not in accordance with the safety requirements Unsuitable locations The locations 1 2 and 3 are not suitable because they are exposed to drafts from windows and doors Location 5 is undesirable because it is in range of plant traffic and within the exhaust air range of a ventilation system 4 Preferred locations Preferred locations 6 7 and 8 are correct because they are in a draft free ...

Page 19: ...2 230V Power Supply X21 Monitor Alarm X20 External Fan The leads can be attached on the outer face of the anti tilt anchor using cable ties Power Receptacles The power receptacles are fused using a T 5A slow blow fuse Power cable X22 X21 X20 High voltage Before starting any work on electrical and electronic components the unit must be disconnected from the power supply The work may only be carried...

Page 20: ... a suitable carrier even for a transport within a building and separate it from the stand Danger of tipping over For transport lift the device only using the lift points shown in the illustration Do not load the drain pan with the weight of the device frame Contusion hazard When lifting the safety cabinet do not put hands or fingers between drain pan and frame ...

Page 21: ...ly to the pertaining blower The exhaust air is released into the environment around the device through the opening 2 Operating panel with cabinet controls alarm system displays and cabinet status display An auxiliary rocker switch for basic BSC window operation is located at the right side in the display area The gas struts 6 secure the front cover in the open state Front cover with integral elect...

Page 22: ...ir system in combination with HEPA filters for downflow and exhaust air forms the basis of the safety system for personal and material protection Personal protection Air aspired from the exterior along the entire working opening at a constant high speed prevents that agents may leak through the working opening of the chamber As the exterior air pressure around the unit exceeds the pressure of the ...

Page 23: ...g Airflow monitoring determines the speed of the airflow in the sample chamber as well as the inflow speed of the air aspired from the exterior through the working opening As soon as air speeds move above or below a specified safety value a signal is transmitted to the alarm system Visual and audible alarm system The warning system constantly monitors the safety relevant device functions inflow sp...

Page 24: ...uct room air and the downflow within the chamber 7 are then blended to make up the blend air 9 The blend air is then filtered proportionally by the downflow filter 5 and supplied as ultrapure air 6 evenly into the sample chamber of the device filtered by the exhaust air filter 2 and released as ultrapure air 1 to the exterior of the device Inlet air protection The air duct between the sample chamb...

Page 25: ...h two separate control elements that operate independently of each other Rocker switch 1 to move the front window up and down Foil keypad to control the equipment functions 2 The status indicators of the display 2 indicate control operations initiated with the control elements In the foil keypad the current status of the cabinet is shown ...

Page 26: ...gh Front Cover Front cover Manual opening of the front cover 1 allows access to the complete sample chamber width with an opening height C It is generally needed for decontamination and introduction of larger accessories NOTE Front cover lockout The front cover is equipped with a safety lockout and can only be open when the front window is completely closed ...

Page 27: ...e work position with opening height A Lowering the front window when the device is deenergized The safety feature is backed up by a battery Should a power failure occur the auxiliary rocker switch see Using the auxiliary Rocker Switch on page 52 can be used to lower the front window completely A minimum working opening B maximum opening height Crushing hazard During movement of the front window do...

Page 28: ...ternal power supply and the two sided feedthroughs 6 for cables and hoses External systems Failure detection systems or gas supply solenoid valves may be connected to the safety cabinet control NOTE The connection of the piping and media valves has to be carried out according to country specific standards and by expert personnel only Combustible gas The use of a gas burner is not recommended If a ...

Page 29: ...e Illumination Figure 9 Workspace Illumination The workspace illumination 2 with fixing screws 1 is equipped with two LED 3 that are installed behind the light dome 4 NOTE The reflector side 5 must be installed upwards so that the radiation side 6 is fully active ...

Page 30: ...alls Both lamp housings are protected by a stainless steel cover 3 By cross radiation of the UV units all surfaces will be disinfected as the shadow zone is reduced The operating time of the UV lamps is preset and can be changed by the operator NOTE Protection from UV radiation As a protection from harmful UV radiation the UV lamps can only be activated if the front window is completely closed ...

Page 31: ... frame above the workspace drain pan Figure 11 Working Area on the Workplate Armrests The working area A for perfect material protection extends over the entire width B and depth C of the workplate 1 The two arm rests 3 are positioned at a distance D 20 cm to each other centrically on the workplate 1 or on the workplate segments The armrests are installed to the second perforation line 2 of the wo...

Page 32: ... Unit Description 32 50161258 HERAsafe 2025 Chapter 4 ...

Page 33: ...sembly and installation performed by the operator are essential for good start up Installing Unit and Accessories Herasafe 2025 Device without stand Place the device without stand onto a sufficiently stable substructure so that the weight of the device frame does not rest upon the drain pan Remove the protective foil from the table tops and arm rests ...

Page 34: ...h stand To assemble the optional stand and to install the device frame to the stand Figure 12 Stand Installation 1 Slide the two crossmembers 2 onto the retaining angles 3 of the sidemembers 1 Secure the crossmembers to the two sidemembers using the screws 4 ...

Page 35: ...t should be levelled only after it has been positioned 1 Remove transport protection foil from the workplate or from the workplate segments 2 Lift the workplate or the workplate segments and place it them onto the front and rear rails in the sample chamber with the wide line of holes facing forward 3 Device without stand Place a bubble level onto the workplate and align the substructure until the ...

Page 36: ...e and must be accessible only to authorized personnel Ideally the outlets should be installed above the safety cabinet and be readily accessible Route the power cables so they do not run across hot surfaces such as exhaust tubing or similar tubing runs Connecting the equipotential bonding If the sample chamber is supplied with media gas water etc the on site equipotential bonding must be connected...

Page 37: ... the location of the device The operator must prepare a test report or request a written test report from the authorized test service NOTE Safety warranty The operational safety of the device particularly the personal and material protection are guaranteed only if all safety functions of the device have been tested and approved Thermo Electron LED will not warrant the operational safety if the dev...

Page 38: ... Start up 38 50161258 HERAsafe 2025 Chapter 5 ...

Page 39: ...D 3 Ventilation reduced ON blue LED 4 Switch display switchover 5 Display 7 Segment 6 Total operating hours 7 Air inlet velocity 8 Downflow velocity 9 Time 10 Rocker switch 11 Switch UV disinfection on off the yellow LED indicates that the UV disinfection routine has been activated if the optional UV lamp is not installed the function of this key is disabled 12 Switch internal sockets on off the b...

Page 40: ... a power failure Display and Functions after a Power Failure After the power supply has been reestablished after a power failure the display shows the values and functions that were last shown prior to the failure The functions that had been selected last will be continued where they had been interrupted Failure Messages Failure messages are shown on the display as text number combinations with th...

Page 41: ...display The contact for the external device connection is not available Work Mode Ensures personal and material protection In this operating mode the work process is run within the sample chamber The device is in the work mode when the front window has been moved into the working position and the airflow is steady The front window is in the working position The green status indicator FRONT WINDOW ...

Page 42: ...atus indicator AIRFLOW NOT STEADY Is illuminated The front window is not in the working position The red status indicator FRONT WINDOW NOT IN WORKING POSITION is illuminated The work space illumination is operational The audible alarm is active The internal power supply is operational If the internal power supply is switched on the status indicator INTERNAL POWER SUPPLY ACTIVATED illuminates Stand...

Page 43: ...temporary operating state of the safety cabinet and automatically disables those functions of the operating panel that are in contradiction to the safety requirements of the switching state The easy operator guidance ensures that all basic functions can be controlled with only a few operating steps and that the safety cabinet can be shifted into the working mode Switch device into work mode Keep t...

Page 44: ...ition the movement is automatically stopped The green status indicator on the display is illuminated The audible alarm signal is off if the airflow is steady 3 If the movement starts above the working position the front window must first be lowered below the working position and then be raised again To lower the front window Keep lower side of the rocker switch depressed 4 Stop downward movement R...

Page 45: ...ly press key Activating Deactivating Internal Power Supply All sockets in the sample room are supplied with power in a switching operation or de energized 1 Switch on power supply Shortly press key The blue status indicator is illuminated 2 Switch off power supply Shortly press key The status indicator goes off Changing UV Desinfection Time This value refers to the set run time of the UV disinfect...

Page 46: ...eep the key depressed until the two digit hour display flashes The minute display shows either A P or no value CET time display The time zone is set at the same time as the hour value First set the time zone sequence CET A P then set the exact hour value 2 While increasing or decreasing the hour value in increments set the time zone Shortly press key or key 3 Scroll thru values Depress key or key ...

Page 47: ...ey as often until LED is white illuminated 2 The value indicates the air inlet velocity in meters per second Display Downflow Velocity The device sensor system permanently monitors the circulating air velocity of the air flow in the sample chamber The currently determined value m s can only be called up in working mode Display velocity value Press key as often until LED is white illuminated NOTE C...

Page 48: ... the front window must not be closed For each following start of the UV disinfection the routine is run with this preset time value 1 Select the function Depress key until ready signal sounds The display flashes the run time that had been selected last 2 Set or change the disinfection time To increase the value in increments Shortly press key or key 3 Scroll thru the values in 30 minutes steps Dep...

Page 49: ...isplayed depending on what has been previously selected Cancel UV Disinfection While the UV disinfection routine is run it can be interrupted at any time 1 Cancelling the routine Shortly press key The yellow LED above key goes off 2 The display shows the current time or operating hours depending on what was previously selected Rocker Switch Figure 15 Rocker switch With the rocker switch the front ...

Page 50: ...he direction of travel 2 To stop the movement upwards release the rocker switch Hold the rocker switch depressed at the bottom To stop the travel movement down release the rocker switch 3 If the front window is not in working position The status indicator is red illuminated The audible warning is switched off when the front window is completely closed 4 If the front window reaches the working posi...

Page 51: ...orking area of the workplate 4 Close the front cover 5 Move the front window to its working position and wait until the airflow has stabilized 6 Then place samples into the chamber 7 To interrupt the work process or for extensive experiment cycles without manual interference switch the device to standby mode When the working opening is completely closed the safety cabinet is sealed aerosol tight O...

Page 52: ... heat Open flames in the sample chamber may impair airflow conditions Work Rules The observance of work rules ensures a minimum of operational safety when handling the safety cabinet Before starting an operation Take off jewelry Put on required personal protective gear e g hand face or body protection Clean and disinfect sample chamber surfaces at regular intervals During an operation Place sample...

Page 53: ...al position the angle between thigh and lower leg should exceed 90 To ensure a compensation between floor and sitting height a footrest DIN 4556 should be used The minimal effective surface of the footrest should be 45 x 35 cm C The slope should be adjustable within a range of 5 to 15 D The adjustable height should extend to a minimum of 11 cm above the floor After finishing an operation Remove sa...

Page 54: ... Preparation 54 50161258 HERAsafe 2025i Chapter 7 ...

Page 55: ... surfaces the workplate and the drain pan 4 Switch the blowers off Shutting the Unit down If the unit is not to be used or stored for an extended period of time it must be completely decontaminated 1 After the device has been decontaminated close the front window completely 2 Disconnect the device from the power supply system Decontamination measures To shut the device down the sample chamber must...

Page 56: ... Shut down 56 50161258 HERAsafe 2025 Chapter 8 ...

Page 57: ...isinfection after a wipe spray disinfection Sterilization with steam can be used for treating the removable stainless steel components Examples of autoclavable components are the bezels of the UV lamps the workplate or workplate segments and the armrests Disinfection with formaldehyde can be performed if a sterile sample chamber is required for the work process This sterilization procedure is mand...

Page 58: ...absorbed by the filters Cleaning 1 Thoroughly remove dirt residues and deposits using a solution of tepid water and dishwashing agent 2 Wipe the surfaces clean using a clean cloth and plenty of clear water 3 Remove the cleaning liquid from the drain pan and wipe all sample chamber surfaces dry Final disinfection 1 Again spray disinfectant on all sample chamber surfaces or wipe the surfaces clean w...

Page 59: ...cabinet The quantity of the formaldehyde used depends on the sample chamber volume of the cabinet version to be disinfected see Technical Data on page 67 Per cubic meter of sample chamber volume at least 5 g formaldehyde must be evaporated with 20 ml water corresponds with 25 ml of a 20 formaldehyde solution The formaldehyde evaporates immediately when its boiling point is reached The required rea...

Page 60: ...clean cloth Cleaning the Front Window For cleaning the front window and for disinfecting it using wipe disinfection the front window can be closed and hinged Cleaning the Drain Pan Clean the drain pan using a solution of tepid water and commercial dishwasher 1 Remove the working plates from the workspace 2 Remove dirt residues and deposits thoroughly 3 Wipe the drain pan clean using a clean cloth ...

Page 61: ...e filter 3 Remove the coarse filter 3 from the bracket 5 and seal it airtight in the disposal container To install the coarse filter The coarse filter material is supplied by the meter and must be fit to match the width of the work space A 4 Cut the coarse filter strip 1 to the required dimension 5 Install the coarse filter into the bracket 5 and make sure that the filter material 3 covers the ent...

Page 62: ... Cleaning and Decontamination 62 50161258 Herasafe 2025 Chapter 9 ...

Page 63: ...ours 1 Remove cover from lamp housing The cover is only pushed onto the lamp casing and may be pulled off easily 2 Rotate the lamp in the socket so that the lamp contacts can be removed from the groove in the socket 3 Insert the new lamp into the socket and rotate until the contacts engage 4 Push the cover onto the lamp casing NOTE Perforated plate The Perforated plate at the blanket of the sample...

Page 64: ...ont Cover Seal Retrofitting and Repairs External communication systems e g failure report systems or components for supplying media such as gas solenoid valves can be retrofitted and integrated into the device control NOTE Front cover seal Check front cover seal in regular intervals at least once a year If seal is damaged call Technical Support NOTE Repairs All retrofitting and repair work are int...

Page 65: ...osal the complete device with filters must be decontaminated by performing a formaldehyde sterilization Component Material Thermal insulation components Polystyrene foam EPS PPS compound Printed circuit boards Enclosed electrical components coated with various plastics mounted on epoxy resin bound boards Plastic components general Note material labeling Exterior housing Steel painted Device backpa...

Page 66: ...ical Electronic Equipment WEEE Directive 2012 19 EU It is marked with the following symbol Thermo Electron has contracted with one or more recycling disposal companies in each EU Member State and this product should be disposed of or recycled through them Further information on Thermo Fisher Scientific s compliance with these Directives ...

Page 67: ...0 59 1 1800 70 9 Depth mm in 627 24 7 Height mm in 780 30 7 Front window Working position mm in 200 7 9 250 9 8 Max opening mm in 780 30 7 Working area height Seat position mm in 750 29 5 Heightable mm in 750 29 5 950 37 4 Stand height mm in 680 26 8 880 34 6 Unit height with stand mm in 2216 87 max 2416 95 Side wall feed throughs Diameter mm in 21 3 0 84 Distance lower edge mm in 135 5 3 Distance...

Page 68: ...fusing A 2x T 5 A On site fusing A Circuit breaker B 16 Fuse T 16 A Equipment fusing 230V A 2 x T16A H Power Power input max W 1675 1675 2010 2010 Protection Protection class I Protection type IP 20 Overvoltage category IEC 1010 EN 61010 II Contamination degree IEC 1010 EN 61010 2 Connection lines Connecting lines cable 2 5 or 5 m 8 2 or 16 4 ft Volume weights and loads Herasafe 2025 0 9 1 2 1 5 1...

Page 69: ...g area module kg lbs 25 55 Max load on overall working area kg lbs 50 110 75 165 75 165 75 165 Airflow system Herasafe 2025 0 9 1 2 1 5 1 8 Air speeds Inflow m s fpm 0 45 88 6 Downflow m s fpm 0 32 63 Air volume 0 9 1 2 1 5 1 8 Overall volume flow m3 h cfm 910 536 1215 715 1520 894 1824 1074 Downflow volume flow m3 h cfm 622 366 829 488 1037 610 1244 732 Inflow air volume flow m3 h cfm 288 170 386...

Page 70: ...IN EN 1822 Material Glass fiber fleece Separability in MPPS 99 995 Separability at 0 3 μm particle size 99 999 Downflow Width mm in 915 36 1220 48 1525 60 1830 72 Depth mm in 457 18 Height mm in 93 3 7 Exhaust Width mm in 457 18 610 24 915 36 Depth mm in 457 18 457 18 457 18 Height mm in 117 4 6 117 4 6 117 4 6 ...

Page 71: ...umidity storage h r 90 Heat dissipation to environment 200 mm 8 access opening Room temperature 20 C kJ s BTU hr 0 13 454 0 15 522 0 22 740 0 25 856 Room temperature rise Above room temperature with window closed K 2 Ergonomics Noise level dB A 57 57 57 57 The noise level was determined in accordance with EN ISO 3744 The sound pressure level was measured at a distance of 1 m in front of the workin...

Page 72: ... Technical Data 72 50161258 Herasafe 2025 Chapter 12 ...

Page 73: ...Herasafe 2025 50161258 73 Device Log Part number Serial number Service number Location Operator s note Date Signature Work carried out Notes Device type ...

Page 74: ... Device Log 74 50161258 Herasafe 2025 Chapter 13 ...

Page 75: ...Herasafe 2025 50161258 75 Certificate of Decontamination ...

Page 76: ... Certificate of Decontamination 76 50161258 Herasafe 2025 Chapter 14 ...

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