ThermoFisher Scientific HERASAFE 2025, Operating Instructions Manual

Page: 13 / 76

Herasafe 2025 50161258 | 13
General Notes |
Chapter 1
Use of the Device
Correct Use
Herasafe 2025:
The safety cabinet is a laboratory device for installation and operation in microbiological
and biotechnical laboratories of safety levels 1, 2, and 3. It has been designed as a Class
II microbiological safety cabinet, in accordance with EN 12469:2000.
Depending on the hazard level of the agents involved, the operator must prepare in writing
appropriate decontamination procedures for the device and the accessories used in the
sample chamber.
Following media should be used:

Vacuum (Rough vacuum 10 E-2 bar / 0,145 psi)

Combustible gas (e.g. Propane)

Non-combustible gas (e.g. Nitrogen)
Incorrect Use
The safety cabinet must not be used in laboratories that do not comply with the
requirements of safety levels 1, 2, and 3.
The unit must not be operated as a Class II safety cabinet if:

no repeat test is performed after changes to the installation conditions or after
modifications to the technical system.

the alarm system of the device has issued a failure message and the cause for the
failure has not been repaired.
The alarm system must not be tampered with or disabled. If alarm system components
have been removed or disabled for service or repairs, the unit must only be released for
operation if all alarm system components are functioning again properly.
The filters installed in the device are not capable of separating gaseous substances.
Therefore, do not work with or store substances in the device:

are toxic which in quantity or concentration,

if a reaction with other substances may result in hazardous toxic concentrations or
formation of toxic gases,

that may form combustible or explosive mixtures in combination with air.