SCIEX 3200 QTRAP, System User'S Manual

Page: 79 / 114

Table 9-1 System Issues (continued)
Symptom Possible Cause Corrective Action
The mass spectrometer
performance has degraded. 1. The ion source conditions
are not optimized.
2. The sample was not
prepared correctly or the
sample has degraded.
3. The sample inlet fittings
are leaking.
1. Optimize the ion source
conditions. Refer to
the section:
Optimize
the TurboIonSpray Probe
Position
or APCI Probe
Optimization .
2. Confirm that the sample
was prepared correctly.
3. Verify that the fittings
are the right size and
type and make sure that
they are tight. Do not
overtighten the fittings.
Replace the fittings if
leaks continue.
4. Install and optimize an
alternate ion source.
5. Contact an FSE if the
issue persists.
Arcing or sparks occur. The position of the corona
discharge needle is incorrect. If the TurboIonSpray probe
is being used, then turn
the corona discharge needle
toward the curtain plate and
away from the stream of
heater gas. Refer to the
section:
Replace the Corona
Discharge Needle .
Table 9-2 Sensitivity Issues
Possible Cause Corrective Action
Sensitivity is Decreased
The ion source parameters are not optimized. Optimize the ion source parameters.
The mass spectrometer is not optimized. Use the Instrument Optimization wizard to
optimize the mass spectrometer.
Mass Spectrometer Troubleshooting
System User Guide
RUO-IDV-05-6475-C
SCIEX 3200 Systems
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