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Physician’s Manual — VNS Therapy Programming Software (8.1)
ramp-up
Gradual increase over approximately two seconds in output
current at the beginning of stimulation greater than 10 Hz in signal
frequency
refractory
Resistant to previous treatment alternatives defined by the treating
physician; generally refers to the epilepsy of patients who have
tried and failed two or more antiepileptic drugs
Note:
Program New Parameter
Settings” on page 21 for
specific reset
parameters.
reset parameters
Parameters to which the Pulse Generator internally programs
when it is reset
SAE
Serious adverse event
signal frequency
Repetition rate of pulses in a stimulation; measured in number of
pulses per second (Hz)
signal OFF time
Interval between stimulations when there is no stimulation;
measured in minutes
signal ON time
Length of time the programmed output current is delivered (not
including ramp-up and ramp-down times); measured in seconds
stimulation parameters
Programmed output current, signal frequency, pulse width, signal
ON time, and signal OFF time
stimulation time
Therapeutic output of the VNS Therapy Pulse Generator; consists
of the signal ON time, plus 2 seconds of ramp-up time and 2
seconds of ramp-down time
SUDEP
Sudden unexplained death in epilepsy
vagus nerve
Either of the pair of tenth cranial nerves arising from the medulla
and supplying mainly the viscera, especially with autonomic
sensory and motor fibers; in this document,
vagus nerve
always
refers to the
left
vagus nerve
