Freeze-dryer Gamma 1-16 LSCplus
Freeze-dryer Gamma 2-16 LSCplus
1 General information
Version 04/2013, Rev. 2.10 of 09/03/2020
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Translation of the original operating manual
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1
General information
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1.1
Importance of the operating manual
A fundamental requirement for the safe and trouble-free operation of the
unit is to be familiar with the fundamental safety instructions and all
possible hazards.
The operating manual includes important information concerning the safe
operation of the freeze-dryer.
This operating manual, and in particular the notes on safety and hazards,
must be observed by all persons operating the unit.
In addition, the local rules and regulations for the prevention of accidents
must be complied with.
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1.2
Intended use
The freeze-dryer has been exclusively designed for the freeze-drying of
solid or liquid products in ampoules, vials or dishes. It is, therefore, solely
intended for this application.
The freeze-dryer is suitable for freeze-drying solid substances and aqueous
solutions (e.g. bacteria and virus cultures, blood plasma, serum fractions,
antibodies, sera, vaccines and pharmaceutical products such as
chloramphenicol, streptomycin, vitamins, ferments and plant extracts for
biochemical tests).
Freeze-drying of solvent-containing products
(non-aqueous media)
With regards of corrosion resistance, the use of some organic solvents in
aqueous solutions with low concentrations is acceptable.
A freeze-dryer is designed to be chemically resistant to most compounds
that are commonly used in freeze-drying processes. However, by
necessity, the freeze-dryer is comprised of several different materials,
some of which may be attacked and degraded by certain chemicals.
The methods of fabrication and/or conditions of exposure of an acrylic door,
as well as the way the chemicals are applied, can influence the results.
Some of these factors are listed below:
• Fabrication: Stress generated while sawing, sanding, machining,
drilling, polishing, and/or forming.
• Exposure: Length of exposure, stresses induced during the life of the
product due to various loads, changes in temperature etc.
• Application of chemicals: by contact, rubbing, wiping, spraying etc.
