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Introduction

 

 
The  7000smz  Tissue  Slicer  by  Campden  Instruments  is  an  oscillating  blade 
microtome  and  is  the  result  of  more  than  25  years  experience  in  the  design  and 
manufacture of tissue slicers. 
The  7000smz  is  a programmable  unit  that allows  the  instrument  to 

‘learn’  a  cutting 

cycle input by the operator and then repeat that cycle a desired number of times. The 
cycle may have a varying speed/distance profile so that particular areas of tissue can 
be sliced at different speeds. 
 
A  number  of  researchers  have  found  that  certain  combinations  of  oscillation 
frequency;  oscillation  amplitude  and  tissue  advance  rate  can  give  superior  slice 
quality for a given tissue. The 7000smz allows these combinations to be developed 
solely by input from the keypad.  
For machine stability and long life the amplitude of cut is related to the frequency of 
oscillation 

– the larger the amplitude, the lower the maximum frequency available and 

vice versa. 
 
Experienced  users  of  oscillating  microtomes  will  no  doubt  be  aware  that  large 
amplitudes  and/or  high  oscillation  frequencies  can  lead  to  excessive  vibration  and 
unstable tissue fluid. The 7000smz instrument benefits in this area by being built on a 
heavy,  rigid  cast  base  giving  exceptional  immunity  to  secondary  vibration 
transmission. 
 
The purpose of this manual is to allow the user to achieve expertise in the use of the 
7000smz  instrument.  Please  read and  understand  the  information  contained  in  this 
manual before using the instrument. Only competent and capable personnel should 
use the instrument. 
 
This  document  should be  retained for future  reference  as  it  contains  the name and 
address of the manufacturer within the EC. 
 
PACKAGING 
Please retain the original packaging for future use. 

Instruments  will  not  be  accepted for  service or  repair

  unless  the unit has  been 

adequately  and  properly  packaged.  Additionally  instruments  will  not  be  accepted 
without prior authorisation and have been certified as being uncontaminated with any 
material  that  may  be  hazardous  to  the  health  of  service  personnel.  A  Returns 
Authorisation and Decontamination Certificate blank form is included in Section 9 of 
this manual and may be photocopied as required. Blank forms can also be obtained 
by contacting Campden Instruments. 
 
 
Campden Instruments Limited 
PO Box 4148 
Loughborough 
Leicestershire 
LE12 7XT 
UK 

Telephone: 

(+44) 0150 9814790 

Fax: 

 

(+44) 0150 9817701 

E-Mail: 

[email protected]

 

 
www.campdeninstruments.com 

 

Summary of Contents for 7000smz

Page 1: ...1 www campdeninstruments com INSTRUCTION MANUAL Vibrating Blade Tissue Slicer NOVEMBER 2019 DCN 2389 Document Ref 7000 v2 4 Eng...

Page 2: ...xis of oscillation 6 10 Settings 7 Options 7 1 Light source 7 2 Magnifier 7 3 Microscope mounting point 8 Maintenance and Service 9 Returns Decontamination Form 10 Technical support Error codes 11 Pac...

Page 3: ...uid The 7000smz instrument benefits in this area by being built on a heavy rigid cast base giving exceptional immunity to secondary vibration transmission The purpose of this manual is to allow the us...

Page 4: ...at maximum speed and only after the uncut tissue has been lowered away from the blade eliminating the possibility of the blade being dragged back across the uncut tissue causing damage Dynamic feedbac...

Page 5: ...An adjustable tissue platen is available as an optional extra The tissue bath is also located and held in place within the outer bath by magnets Inner and outer tissue bath background with standard ti...

Page 6: ...6 A lower power 2x magnifying lens assembly can be fitted as an alternative to the microscope 7000smz fitted with magnifying glass and cold light source...

Page 7: ...to an acute cutting edge Because of the relative softness of stainless steel for optimum performance it is recommended that stainless steel blades should be used once only or at a maximum changed ever...

Page 8: ...rinsed with clean water on a regular basis The specimen platen and the inner stainless steel bath as shown in the illustration below are autoclavable The specimen holder is located by a circular magn...

Page 9: ...be set for your particular voltage supply The voltage is set by prising out the fuse holder drawer and re inserting it such that the voltage legend for your supply is aligned with the mark on the inl...

Page 10: ...is the normal operating display Press the MENU key again and the display will change to that shown Use the or keys to scroll to the line SETTINGS Then scroll to the line EDIT USER NAME and select Use...

Page 11: ...changes to the oscillating frequency amplitude and section thickness will be remembered under that user name so that when that user comes back to the instrument and selects that user name those settin...

Page 12: ...eys can now be used to change the parameter s value Press the MENU key to confirm and store the change Frequency settings can be changed in 5Hz steps and amplitude can be changed in 0 25mm steps Note...

Page 13: ...ove the bath move the clamp lever to the left and pull the bath away from the instrument Pressing LOAD BATH keypad will cause the table to rise to a preset nominal position The display will then rever...

Page 14: ...Section 6 2 and scroll to the EXIT MENU line and press the MENU key If necessary load a bath to the table and press the LOAD BATH key The table will raise the bath to a nominal position and the opera...

Page 15: ...ey to reset the height datum Press the HEIGHT key once more to exit Bringing the specimen to the start position Cutting a slice Press the ADVANCE key and using the rotary knob to control the advance s...

Page 16: ...d then raised once more by the thickness of the section in readiness for another cut When the cutting head has been retracted to the start position the section thickness will be highlighted on the dis...

Page 17: ...via the manual slice procedure the display will indicate NO SLICE PROFILE HAS BEEN CREATED This display will time out and revert to the basic manual operating screen When a satisfactory cut window has...

Page 18: ...ection 6 10 If you try to operate the instrument in the automatic mode without having previously set a cutting profile via the manual slice procedure the display will indicate NO SLICE PROFILE HAS BEE...

Page 19: ...ow the instructions on screen to CONTINUE or ABORT the procedure Pressing MENU at this stage will allow access to menu functions permitting changes to frequency and amplitude etc Note that the EMERGEN...

Page 20: ...ment has been halted by use of the Emergency Stop facility it must be reset before operations can continue Twist the red Emergency Stop button clockwise to unlatch it When the button is unlatched the...

Page 21: ...designed so that the blade may be safely handled without the effective cutting length of the blade edge being exposed to possible damage or injuring the operator After carefully unwrapping the blade...

Page 22: ...trument this incorporates a magnet and can simply be fitted over the blade with the magnet holding it in position See the following illustration This will provide some protection to the user and reduc...

Page 23: ...ecured by two screws to the oscillating faceplate A third screw locks the blade holder in position once the alignment procedure has been completed See the illustration below Fit the blade holder as sh...

Page 24: ...in its optimal position relative to the calibration device for best alignment evaluation To enter the alignment routine press the LOAD BATH key and hold for 2 seconds The bath table will be moved to...

Page 25: ...hexagonal driver Tighten the lower screw Conversely the blade holder can be tilted in a counter clockwise direction by turning the adjusting screw counter clockwise Press SLICE to set the blade vibra...

Page 26: ...26 Correct any problems and press SLICE to retry...

Page 27: ...r keys Press the MENU key to confirm the change Use the or keys to scroll to line EXIT MENU and press the MENU key to get back to the basic menu display 2 When in an automatic slice mode the park posi...

Page 28: ...strated below The light source can be switched on and the light intensity controlled via a combined press button on the body of the light source where the flexible arms are mounted A brief press will...

Page 29: ...should then be fixed to the top of the instrument cover using the screws provided Do not over tighten the screws This is illustrated below If you also have the optional light source the magnifier sho...

Page 30: ...cope free from vibration The Campden CL200 cold light source see above can be fitted directly to the top of the 7000smz 2 independently of the microscope For ease of access you should fit the light so...

Page 31: ...t be accepted for service or repair unless the unit has been adequately and properly packaged Additionally instruments will not be accepted without prior authorisation and have been certified as being...

Page 32: ...eria fungi etc YES NO 2 Radioactive Sources YES NO IF YES DO NOT RETURN 3 Chemical Hazard mercury salts acids bases etc YES NO 4 Rabies BSE CJD nCJD etc YES NO 5 Any Other Hazard PLEASE SPECIFY YES NO...

Page 33: ...rial number Build date Blade run time Software revision code Any error codes that you may have witnessed This information may be readily accessed from the basic menu screen as follows Use the or keys...

Page 34: ...n obstructed restart the instrument and carefully drive the blade away from the obstruction If the error occurs repeatedly during normal use contact Technical Support for advice Code 8 Instrument over...

Page 35: ...35...

Page 36: ...Specimen holder 1 off Opti Cal optical Calibration unit 1 off Stainless steel blades 10 off 7550 1 SS Ceramic blades 2 off 7550 1 C Cross head Philips PoziDriv screwdriver 1 off Hexagonal drivers 2 o...

Page 37: ...nt adjustable specimen holder 7000 4 2 Blade holders 5000mz Blade holder For 7000smz prior to serial number 7000smz 020 and 5000mz prior to s n 5000mz 1004 7000 5 1 Blade holder special angle 7000 5 2...

Page 38: ...cutting head 37 mm nominal Blade oscillation frequency 7000smz Minimum 50 Hz Maximum 120 Hz amplitude dependent Frequency step size 5 Hz Blade oscillation amplitude 7000smz Minimum 0 5 mm nominal Max...

Page 39: ...ibility Directive 89 336 EEC The Low Voltage Directive 73 23 EEC 2 UK Regulations The Supply of Machinery Safety Regulations 1992 SI 1992 3073 Electricity at Work Regulations 1989 3 European Standards...

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