HFA3 Instructions for Use
2660021166131 Rev. A 2018-11
Data, Tests & Reports
6-14
Progression Analysis Probability Plots
The Progression Analysis Probability Plot compares the changes between the Baseline and
Follow-up tests and highlights points that have worsened by an amount that exceeds the variability
in all but the most variable 5% of glaucoma patients in a reference population.
• A single, solid dot indicates a point not changing by an amount that exceeds the test-retest
variability observed in a reference population.
• A small open triangle
identifies a degree of deterioration expected less than 5% of the
time at that location in a reference population of stable glaucoma patients; that is,
deterioration at the 5% level (p < 0.05). This symbol is used when the change was not seen on
a previous Follow-up test.
• A half-filled triangle
identifies a point changing by an amount that is worse than all but the
most variable 5% of glaucoma subjects in a reference population and that is repeated in two
consecutive Follow-up tests.
• A solid triangle
identifies a point changing by an amount that is worse than all but the
most variable 5% of glaucoma subjects in a reference population and that is repeated in three
consecutive Follow-up tests.
• An
X
signifies that the data at that point was out of range for analysis.
Note: Pattern Deviation plots and GPA Progression Analysis Probability plots are not shown for
severely depressed visual fields (MD less than or equal to 20 dB).
VFI Plot
The VFI Plot graphs the VFI values of all tests included in GPA analysis as a function of the patient’s
age, and provides a linear regression analysis of the VFI over time (5 tests over 3 years or more are
required). VFI values from Full Threshold tests are represented by open squares, and VFI values from
SITA tests are represented by filled squares.
To the right of the VFI Plot is the VFI Bar, indicating the patient’s current VFI value. The VFI Bar will
graphically indicate the 3 to 5 year projection of the linear regression line, shown as a broken line.
The length of projection is equal to the number of years of GPA data available, up to a maximum of
5 years.
Note: GPA reports also include the GPA Alert. In cases where 3 or more points show deterioration in
at least 2 consecutive tests, the progression analysis indicates “Possible Progression.” In cases
where 3 or more points show deterioration in at least 3 consecutive tests, the progression analysis
indicates “Likely Progression.” When neither of the foregoing conditions applies, a message of “No
Progression Detected” is displayed.
GPA Analysis
Only SITA tests may be chosen initially for GPA analysis. You may mix any combination of
SITA-Standard, SITA-Fast or SITA Faster tests to create a GPA analysis. The HFA3 will automatically
choose the two oldest compatible tests to be the Baseline. Tests displaying high False Positives
≥
15% are excluded by default from GPA analysis. You can manually change the default Baseline tests
or exclude specific tests.
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