Section I – CD AutoPlus Maintenance
CD14 Tester & CD AutoPlus Autosampler User Guide—75-108-800 Rev. B—31 May 2021
103 of 130
EAR99 technology subject to restrictions on cover page.
CD AutoPlus General Cleaning
The autosampler and collector have been designed to be a low
maintenance instrument. In general, the instruments are
maintained by wiping clean after each use, as well as running
DI-grade water through the units after each test to clean the
lines.
The exterior of the instrument should be periodically wiped down
with a damp cloth. Frequency of cleaning depends on the
instrument usage and operating environment. If there is spillage
on the unit, clean it up as soon as possible.
Cleaning Method for Tubing, Valves and Syringes
Supply DI-grade water (or better) to the cleanest source on the
autosampler. If media replace is used, supply the DI-grade water
to source C. From the cleanest source, pump out to the
dissolution testers and collectors. This will push any debris away
from the valves and help prevent any damage or clogs from
occurring.
Syringe Replacement
Replace syringe plungers when the maintenance log indicates
100,000 cycles or as needed. After replacing syringes, volume
calibration should be performed. DI or better quality water
should be used for this procedure.
1.
Remove the front cover of the CD AutoPlus.
2.
Using the autosampler controls, select the manual
control option and load the syringe with 2 mL of water.
3.
Remove the shoulder screw at the bottom of the
syringe.
4.
Using the autosampler controls, select the manual
control option and load the syringe with 5 mL of water.
5.
Gently unscrew the syringe by grasping the barrel and
turning it clockwise.
6.
Install the new syringe by screwing it in
counterclockwise.
NOTE: When the syringe contacts the manifold, turn it
no more than 45 degrees in order to ensure a good
seal and not damage the valve.
