Magnis and Magnis Dx NGS Prep System User Guide
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Product Description
The Magnis NGS Prep System is an automated liquid handling system for next generation
sequencing library preparation and/or target enrichment of human nucleic acid samples.
Intended Use
The Magnis Dx NGS Prep System is an automated liquid handling system for next generation
sequencing library preparation and/or target enrichment of human nucleic acid samples.
The Magnis Dx NGS Prep System is to be used only by operators trained in laboratory techniques
and procedures.
The customer is responsible for validation of assays and compliance with regulatory
requirements that pertain to their procedures and uses of the instrument.
Principle of the NGS Prep Procedure
The Agilent Magnis/Magnis Dx NGS Prep System is a liquid handler that offers start-to-finish
automation of library preparation and target enrichment protocols for next generation sequencing
(NGS). The starting material is fragmented genomic DNA (gDNA) purified from a cell or tissue
sample, blood sample, or formalin-fixed paraffin-embedded (FFPE) sample. The end result is a
target-enriched DNA library ready for sequencing.
The hardware components make up the instrument. See
for a list of these components.
The instrument is controlled through the software component of the system, which is displayed
and operated through the LCD touchscreen. Chapter 3
include instructions on setting up and operating the Magnis/Magnis Dx
NGS Prep System using the software. Chapter 6
, “Software User Interface Reference,”
provides a
description of each individual software screen, detailing the purpose of each feature on the
screen.
Limitations of Use
The Magnis/Magnis Dx NGS Prep System has been validated for use with Agilent Magnis NGS
kits.
