Thermo Scientific Vanquish VF-D20, Operating Manual, Page: 25 / 182

2 • Safety
Vanquish Charged Aerosol Detectors Operating Manual Page 25
2.4 Solvent and Additive Information
To protect optimal functionality of the Vanquish system, observe these
recommendations on the use of solvents and additives:
• The system must be used with reversed-phase (RP) compatible
solvents and additives only.
TIP The Vanquish charged aerosol detector can also be used with
normal-phase (NP) compatible solvents and additives if the other
modules in the Vanquish system are compatible for normal-phase
applications.
Before you use normal-phase solvents and additives, make sure that
all modules and components in the system are compatible for
normal-phase applications. Refer to the
Operating Manuals
for the
other modules in the system.
•
Use only solvents and additives that are compatible with all parts in
the flow path.
For details about the materials that are used in the flow path of the
detector, see the
Specifications
chapter. For information about the
materials that are used in the flow path of the other modules in the
Vanquish system, refer to the
Specifications
chapter in the
Operating Manual
for the module.
♦ For the charged aerosol detector
Observe the
Mobile Phase Guidelines for the Detector
in
section 6.5.1, page 95 .
♦ For other modules in the Vanquish system
Observe the general guidelines and recommendations in the
Vanquish System Operating Manual
on the use of solvents and
additives in the chromatography system.
•
Allowed ranges and concentrations for the charged aerosol detector:
♦ pH range: 2-9.5
♦ Volatile buffer concentration: less than or equal to 0.1 mol/L
♦ Chloride concentration: Not recommended
• Observe the following for pH values higher than 9.5:
Avoid using mobile phases with a pH value higher than 9.5. They can
impair the functionality and performance of the nebulizer.