MSD SECTOR Image 2400, Instrument Manual

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Introduction 7
Introduction
1
MESO SCALE DISCOVERY
®
(MSD) develops, manufactures, and markets biological assays that provide cost-effective and valuable
information to scientists in drug discovery, therapeutic screening, and life science research. MSD's product portfolio is based on
MULTI-ARRAY
®
technology, a proprietary combination of patterned arrays and electrochemiluminescence detection that results in
exceptional sensitivity, speed, dynamic range, and convenience.
MSD
develops, manufactures, and markets detection instrument systems as well as a line of assay kits for use with these instruments,
a proprietary line of reagents, and custom microplate printing and assay development services. MSD MULTI-ARRAY microplates are
available in 96-, 384-, and 1536-well formats with standard or high-binding surfaces. MSD plates may be purchased uncoated or
coated with proteins such as streptavidin or avidin, with anti-species antibodies such as goat anti-mouse or goat anti-rabbit, or with
antibodies against specific analytes. Custom coatings and surface treatments are available.
MSD MULTI-ARRAY plates are available as single spot (single assay) plates and as MULTI-SPOT
®
plates with patterned spot arrays in
each well. MULTI-SPOT plates measure multiple analytes simultaneously in a single well, increasing throughput and enabling novel
assay panels.
For more details and information about applications, please visit the MSD website at
www.mesoscale.com .
1.1 Intended Audience
This manual is for all users of the SECTOR Imagers. Users should understand general computer and Microsoft ® Windows terminology,
and be familiar with standard laboratory practices. The intended users of the SECTOR Imagers are those conducting research in the life
sciences.
The SECTOR Imager 2400/2400A and SECTOR Imager 6000 share many features. Throughout this manual, the reader should assume
that a feature is common to all instruments unless otherwise noted. This manual describes how to operate SECTOR Imagers and
acquire data. The analysis of this data is treated in a separate manual: DISCOVERY WORKBENCH
® User Guide.
1.2 How to Use This Manual
This publication is intended as reference and instruction for users of MSD SECTOR Imager 6000 (models 1200 and 1201) and
SECTOR Imager 2400/2400A (models 1250/1251). These instruments are designed to read MSD MULTI-ARRAY and MULTI-SPOT
plates.
This manual is divided into chapters containing main topics and subsections. Use the hyperlinked Table of Contents to find topics of
interest quickly. The List of Figures and List of Tables hyperlink to the images and tables that enhance understanding of written
information in this manual. The Appendix contains supplemental information on troubleshooting, instrument specifications, safety
symbols, regulatory information, and labels.
The term SECTOR Imager will be used to describe the SECTOR Imager 2400/2400A and the SECTOR Imager 6000 when the feature
being described is substantially the same. Differences between SECTOR Imagers will be described explicitly where appropriate.