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Biotage
®
Flash 75/150 User Manual | © Biotage 2018
System Components
System Components
Prepacked Biotage
®
Flash Cartridge
The prepacked flash cartridge from Biotage is the key to the
radial compression module’s improved performance. Flash
cartridges are available in a wide variety of sizes for optimum
separation of samples ranging from 50 mg to 8 kg. Biotage
offers Flash 75 and Flash 150 cartridges and radial compression
modules for samples up to 1000 grams; see Table 1 below.
*
Each flash cartridge is prepacked as standard with normal
phase silica, C18-bonded silica, amine-functionalized silica,
or activated carbon, and is individually wrapped with a water
repelling plastic film to minimize water vapor adsorption.
Each case of cartridges includes certificates of compliance and
conformance with detailed information for your records in GLP
or cGMP environments.
The flash cartridge itself is made from FDA compliant, medium
density polyethylene. The flow distribution plate and 10 μm
porosity frits are also fabricated from FDA compliant polyethylene.
*
This user manual deals specifically with the Flash 75 and 150 cartridge
series. For information on additional cartridge diameters, contact Biotage.
See contact information on the back of this document or visit our website
www.biotage.com.
Radial Compression Module
The radial compression module (see Figure 3), together with
the flash cartridge, is the heart of the system. It is an anodized
aluminum barrel with an instant-tight fitting for connection to
the inert gas outlet on the AM-190 manifold (see page 3).
The safety features on the barrel include a safety relief valve that
activates at pressures in excess of 110 psi (7.6 bar) for Flash 75
and 150 psi (10.3 bar) for Flash 150, and a red pressure indicator
that sticks out when there is more than 20 psi (1.4 bar) of inert
gas pressure inside the radial compression module (see Figure 2).
Figure 2. The pressure indicator sticks out when the pressure inside the
radial compression module is more than 20 psi (1.4 bar).
Figure 3
Safety relief valve
Viton O-ring
Anodized aluminum barrel
Pressure indicator
Radial compression inert gas inlet
Stainless steel head assembly
Fraction collection outlet
Portable cart
(only Flash 150)
V-band clamp
V-band clamp
Stainless steel head assembly
Three-way valve
Prepacked cartridge
Viton O-ring
. The components of the Flash 150 radial compression module.
The Flash 75 module has the same features but instead of being delivered
with a portable cart it has mounting pads on the side of the barrel for easy
connection to lab scaffolding or support bars.
A Viton O-ring sits inside a groove in the top lip of the barrel and
seals the radial compression module against leakage of gas.
The bottom opening of the barrel has an identical groove and
O-ring. Two replacement O-rings are provided with the start-up
kit (see page 5).
The Flash 150 radial compression module comes with a portable
cart with casters. The Flash 75 barrel is easily attached to standard
½" (12.7 mm) Flex-Frame type laboratory mounting bars using
a pair of standard mounting rods that screw into the mounting
pads on the side of the barrel. With the rods in place, the module
can be secured with standard mounting clamps (not included).
Specification
Flash 75M
Flash 75L
Flash 150M
Flash 150L
Size D x H
75 x 150 mm (3" x 6")
75 x 300 mm (3" x 12") 150 x 300 mm (6" x 12") 150 x 600 mm (6" x 24")
Mass of Biotage
®
KP-Sil Silica (approx.) 0.4 kg
0.8 kg
2.5 kg
5.0 kg
Column Volume (approx.)
0.5 liter
1.0 liter
4.3 liters
8.6 liters
Sample Size
Up to 80 grams
Up to 160 grams
Up to 500 grams
Up to 1000 grams
Table 1. The specifications of the Flash 75 and Flash 150 cartridges.
Summary of Contents for Flash 150
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