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19
How to Use the System
Figure 25
Sliding
lock ring
Bladed
“leaves”
. The cartridge extraction tool simplifies the removal of a used
cartridge from the radial compression module.
11. Clean the radial compression module using a detergent
suitable for the residues and allow it to dry.
Note:
If an O-ring at the top or the bottom of the barrel
shows any signs of wear or damage, replace it. Two spare
O-rings are supplied with the system.
Figure 26. The O-ring at the top of the radial compression barrel.
12. If the Flash 75/150 system is not used for a longer period
of time or you want to change solvent before the next run,
please empty the solvent tube that is connected to the
solvent reservoir.
Note:
The solvent tube contains solvent; please ensure
to take the necessary precautions to avoid spillage when
disconnecting the tube.
Clean the Sample Injection
Module (Biotage
®
SIM)
1. Ensure that the three-way valve on the radial compression
module and the two-way valve on the solvent reservoir are
closed.
2. Ensure that the inert gas supply is turned off and that the
three valves on the AM-190 manifold are set to their off/vent
positions (see Table 2 on page 3).
3. Disconnect the two grounding clips attached to the SIM
(item 3 and 4 in Figure 16 on page 13).
4. Loosen the clamp on the SIM and remove the top assembly
(clamp, lid with the three-way valve, and sanitary gasket).
5. Disconnect the SIM outlet tubing from the SIM.
6. Remove the SIM from the chain clamp.
7. If a pre-adsorbed sample was used:
a. Remove the upper frit in the SIM body; use a screwdriver
or similar tool to push through the frit and pull it out.
b. Scrape out the pre-adsorbent media using a spatula or
similar tool and dispose of it in a safe manner.
8. Remove the lower frit in the SIM body; use a screwdriver or
similar tool to push through the frit and pull it out.
9. Unscrew the lower half of the frit holder and remove and
dispose the sealing ring and frit in a safe manner; see
Figure 22 on page 16.
10. Clean the SIM body and the frit holder thoroughly using a
detergent suitable for the residues and allow it to dry.
11. When the SIM is dry, reassemble it.
12. Place the SIM back onto the fume hood’s mounting bars
using the chain clamp.
13. Re-attach the two grounding clips as shown in Figure 16 on
page 13.
Summary of Contents for Flash 150
Page 1: ...Biotage Flash 75 150 User Manual ...
Page 34: ...32 Biotage Flash 75 150 User Manual Biotage 2018 Notes Notes ...
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