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PTFE vs. UHMWPE for syringe seals and valve plugs
Reference information
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PTFE vs. UHMWPE for syringe seals and valve plugs
Valve plugs and syringe seals may be PTFE or UHMWPE. Each of these
materials has its advantages and disadvantages. These are summarized
in Table 9-5.
Table 9-5: PTFE vs. UHMWPE
Material
Advantages
Disadvantages
PTFE
• Best chemical resistance. Very
inert.
• Very soft (good for sealing)
• Very low seal drag due to its
low friction properties
• Not well suited for crystalline
reagents such as buffers.
• Easily scored/damaged.
• Can shed over time (although we
specify the best PTFE available to
avoid this potential issue).
UHMWPE
• Very good chemical resistance.
• Best abrasion resistance.
• Extremely durable material yet
fairly soft so well suited for
long-lasting seals.
• Longest life.
• Will not shed over time.
• Well suited for crystalline
reagents such as buffers.
• Higher seal drag.
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