background image

19.  Carefully close the door on the front of the outer 

support container. Before latching the door shut, 
ensure that one operator holds the front tubing line 
sets above the door so none of the tubing is caught 
as the door closes (Figure 27). Ensure that the row of 
probe ports is aligned just below the bottom front of 
the door (Figure 28).

21.  Begin slowly filling the BPC with air to allow the drive 

train to separate from the inside of the BPC. This also 
aids in the proper alignment of the BPC in the outer 
support container.
•  Attach the air supply to one of the sparging gas 

inlet lines after removing the bubble wrap from the 
line set.  

Note:

 Air pressure to the gas line on the DynaDrive 

S.U.B. BPC should not exceed 34 mbar (0.5 psi).

•  Begin air inflation through one of the sparging gas 

lines. Times will vary based upon flow rate and inlet 
pressure.

WARNING:

 

The BPC is not rated as a 

pressure vessel.

 DO NOT EXCEED

 34 

mbar (0.5 psi) within the BPC or the system 
could fail, causing personal injury or damage 
to equipment. DO NOT leave the BPC 
unattended while inflating. Consult your sales 
representative for recommended air flow rates. 
The operating pressures at the level of the 
DynaDrive S.U.B. are of primary importance, 
and these values must be adhered to.

22.  Check the BPC to ensure that the foam probe is 

hanging freely, and is not entangled in the drive train.

23.  Clamp (or slide on, from the front) the black top tab 

holders on both sides of the outer support container 
(Figure 31). Attach the two hanging tabs at the top front 
side of the BPC to the black plastic pins on the top 
front of the outer support container.  

Figure 26. BPC bottom hanging tab 
attached to bottom pin.

Figure 30. Closing and latching the top door latch.

Figure 27. Lifting tubing line sets above 
the door while closing.

Figure 28. Probe port row aligned 
underneath closed door (BPC shown filled).

20.  Close and secure the latches at the top and bottom 

of the door (Figure 30).

8

Содержание HyPerforma DynaDrive 500 L

Страница 1: ...d not be moved by pulling of any kind The Thermo Scientific HyPerforma DynaDrive S U B may not be installed in a potentially explosive atmosphere as set forth in the applicable EU ATEX Directive It is the responsibility of the end user to review and understand the potential dangers listed in the ATEX 2014 34 EU guidelines Static electricity may build up in BPCs BioProcess Containers BPCs may act a...

Страница 2: ...erated under traditional eukaryotic cell culture conditions A general understanding of bioreactor systems and their operation is important prior to using the system for the first time Read and understand this user s guide before operating failure to do so could result in injury and potential loss of product Only trained operators should be allowed to operate the equipment For complete warnings saf...

Страница 3: ... ring if it is present Remove the tri clamp 2 Loosen the lockout nut using an adjustable or 1 25 in wrench not supplied until the nut is tight against the base or leg of the S U B Repeat this process for each load cell until all of the lockout nuts are disengaged from the lockout posts Do not reinstall the tri clamp 3 At this point the DynaDrive S U B hardware is ready to be prepared for BPC loadi...

Страница 4: ... jacket Figure 4 The inlet is typically on the right side if you are facing the connectors refer to the permanent labels on the inlet and outlet lines Figure 4 Attaching water jacket port using a tri clamp Note Refer to the TCU manufacturer s guidelines for detailed TCU setup information 10 Use the tri clamp fitting to attach the water jacket inlet outlet ports to the bottom of the outer support c...

Страница 5: ...se a safety cutter to carefully open the outer polybag Figure 10 Take care to not damage the BPC Figure 12 Pushing button on hub cover Figure 13 Hub cover opened Figure 14 Raising BPC lift lever Figure 6 Slitting open taped sides of the BPC box Figure 7 BPC secured to cardboard insert in box Figure 8 Carefully lifting out the BPC Figure 9 Folding up flaps on the insert 5 While another operator hol...

Страница 6: ...ngaged by attempting to push the lever back up If the hub is not locked the hub will fall out and the arm will raise 12 Locate the bottom hub at the bottom center of the BPC Pull the hub toward the center cutout at the bottom front of the outer support container Once the hub is aligned with the correct cutout slide it toward the back of the DynaDrive S U B until you feel it shift into place Figure...

Страница 7: ...the front linesets to keep them from tangling use the motor lift controller see the user s guide DOC0090 for information on using the motor lift controller to raise the pneumatic motor lift Figures 23 and 24 After raising the motor lift to its highest position turn the lock dial on the motor lift controller Note The controller cannot be locked unless the motor lift has been fully raised Figure 23 ...

Страница 8: ...ot rated as a pressure vessel DO NOT EXCEED 34 mbar 0 5 psi within the BPC or the system could fail causing personal injury or damage to equipment DO NOT leave the BPC unattended while inflating Consult your sales representative for recommended air flow rates The operating pressures at the level of the DynaDrive S U B are of primary importance and these values must be adhered to 22 Check the BPC t...

Страница 9: ...e air before this is possible 25 While the BPC continues filling with air remove all bubble wrap and polybags from the line sets 26 Remove the polybag from the drain line set position the line clamp as close as possible to the BPC port and then close the clamp Use a cable tie around the clamp to ensure it does not open 27 Remove the plastic insert located in the thermowell if present 28 Insert the...

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