1.7.1 Product (daughter) ion spectrum
Product ion spectrum is the most commonly used MS/MS operating mode. You can specify an
ion of interest for fragmentation in the collision cell, yielding structural information.
Figure 1–5: Product ion spectrum
MS1–Static (at precursor mass)
Collision cell–Fragment precursor ions and pass all masses
MS2–Scanning
1.7.1.1 Typical applications
You typically use product ion spectrum for the following applications:
• Method development for MRM screening studies:
• Identifying product ions for use in MRM transitions.
• Optimizing CID tuning conditions to maximize the yield of a specific product ion to be used
in MRM analysis.
• Structural elucidation.
1.7.2 Precursor (parent) ion spectrum
Figure 1–6: Precursor ion spectrum
MS1–Scanning
Collision cell–Fragment precursor ions and pass all masses
MS2–Static (at product mass)
January 10, 2022, 715006200 Ver. 01 (previously released as Rev. A)
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