Waters SYNAPT G2, Operator'S, Overview And Maintenance Manual

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Cleaning the source components 5-21
Cleaning the source components
Clean the sample cone and cone gas nozzle (see page 5-21 ) when these
conditions apply:
• The sample cone and cone gas nozzle are visibly fouled.
• LC and sample-related causes for decreased signal intensity have been
dismissed.
If cleaning the sample cone and cone gas nozzles fails to increase signal
sensitivity, also clean the extraction cone (see page 5-31 ).
If cleaning the extraction cone fails to increase signal sensitivity, clean the ion
block and isolation valve (see page 5-38 ).
If cleaning the ion block and isolation valve fails to increase signal sensitivity,
also clean the source T-Wave ion guide assembly (see page 5-49 ).
Cleaning the sampling cone assembly
You can remove the sampling cone assembly (comprising the sample cone,
O-ring, and cone gas nozzle) for cleaning without venting the instrument.
Removing the sampling cone assembly from the source
Required materials
Chemical-resistant, powder-free gloves